FAM azide, 6-isomer | 1386385-76-7

Product Introduction

FAM azide, 6-isomer is a highly intricate and cutting-edge fluorescent labeling reagent renowned for its remarkable efficacy in the precise and targeted labeling of intricate biomolecules employed in the realm of biomedicine. Widely acknowledged for its unparalleled aptitude to seamlessly conjugate with proteins, nucleic acids, and peptides, particularly facilitating transformative applications like cellular imaging, flow cytometry, and ingenious drug delivery systems. By harnessing this remarkable product, scientists unlock unprecedented opportunities to decipher intricate biological processes, delving into the realms of profound protein-protein interactions and intricate cellular signaling pathways.

Chemical Information
Synonyms	N-(3-azidopropyl)-3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxamide; 6-Carboxyfluorescein azide; 6-FAM-Azide min. 95 %; 4-((3-AZIDOPROPYL)CARBAMOYL)-2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)BENZOESAURE; N-(3-Azidopropyl)-3-oxo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxamide
Purity	NMR 1H, HPLC-MS (95%)
IUPAC Name	N-(3-azidopropyl)-3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxamide
Canonical SMILES	C1=CC2=C(C=C1C(=O)NCCCN=[N+]=[N-])C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O
InChI	InChI=1S/C24H18N4O6/c25-28-27-9-1-8-26-22(31)13-2-5-16-19(10-13)24(34-23(16)32)17-6-3-14(29)11-20(17)33-21-12-15(30)4-7-18(21)24/h2-7,10-12,29-30H,1,8-9H2,(H,26,31)
InChI Key	JQDJGCPZDAATOX-UHFFFAOYSA-N
Solubility	soluble in polar organic solvents (DMF, DMSO, alcohols)
Appearance	yellowish crystals

Computed Properties
XLogP3	4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	458.12263431 g/mol
Monoisotopic Mass	458.12263431 g/mol
Topological Polar Surface Area	119Ų
Heavy Atom Count	34
Formal Charge	0
Complexity	821
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Patents

Publication Number	Title	Priority Date
US-2020190045-A1	Ferroportin inhibitors and methods of use	2018-12-13