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5-Carboxyfluorescein diacetate | 79955-27-4
| Catelog Number | F04-0034 |
| Category | Fluorescein FAM |
| Molecular Formula | C25H16O9 |
| Molecular Weight | 460.394 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| F04-0034 | 500 mg | $228 |
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Product Introduction
5-Carboxyfluorescein diacetate is a non-fluorescent, cell-permeant hydrophobic probe that is used in the synthesis of rhodamines.
Chemical Information |
|
|---|---|
| Synonyms | 5-CFDA |
| Purity | >93.0%(T)(HPLC) |
| IUPAC Name | 3',6'-diacetyloxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid |
| Canonical SMILES | CC(=O)OC1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)C(=O)O)C(=O)O3)C5=C(O2)C=C(C=C5)OC(=O)C |
| InChI | InChI=1S/C25H16O9/c1-12(26)31-15-4-7-19-21(10-15)33-22-11-16(32-13(2)27)5-8-20(22)25(19)18-6-3-14(23(28)29)9-17(18)24(30)34-25/h3-11H,1-2H3,(H,28,29) |
| InChI Key | WPUZGNPQMIWOHE-UHFFFAOYSA-N |
| Appearance | Solid |
| MDL Number | MFCD00036872 |
Product Specification |
|
|---|---|
| Condition To Avoid | Heat Sensitive |
| Storage | <0 °C |
| GHS Hazard Statements | Not Classified Reported as not meeting GHS hazard criteria by 38 of 39 companies (only ~ 2.6% companies provided GHS information). For more detailed information, please visit ECHA C&L website. |
Computed Properties | |
|---|---|
| XLogP3 | 3.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 5 |
| Exact Mass | 460.07943208 g/mol |
| Monoisotopic Mass | 460.07943208 g/mol |
| Topological Polar Surface Area | 125Ų |
| Heavy Atom Count | 34 |
| Formal Charge | 0 |
| Complexity | 828 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22541068 | 2012-05-24 | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions | Journal of medicinal chemistry |
| 22558349 | 2012-01-01 | Regulation of epithelial cell morphology and functions approaching to more in vivo-like by modifying polyethylene glycol on polysulfone membranes | PloS one |
| 22027652 | 2011-12-01 | Functional defect caused by the 4544G>A SNP in ABCC2: potential impact for drug cellular disposition | Pharmacogenetics and genomics |
| 21609321 | 2011-08-01 | Function of MRP1/ABCC1 is not dependent on cholesterol or cholesterol-stabilized lipid rafts | The Biochemical journal |
| 20880209 | 2011-01-01 | Development of a nondestructive fluorescence-based enzymatic staining of microcolonies for enumerating bacterial contamination in filterable products | Journal of applied microbiology |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| KR-20220158291-A | A pharmaceutical composition containing cell-transducing Inorganic Pyrophosphatase 1 fusion protein for preventing or treating motor neuronal disorder | 2021-05-20 |
| KR-20220147167-A | Pharmaceutical composition for treating cerebral ischemia containing cell-transducing PGAM5 fusion protein | 2021-04-26 |
| KR-20220142557-A | Pharmaceutical composition for treating cerebral ischemia containing cell-transducing CRYM fusion protein | 2021-04-14 |
| JP-2022037654-A | Compounds localized in the Golgi apparatus and their use | 2020-08-25 |
| JP-2021138671-A | PPM1D inhibitor | 2020-03-09 |
Applications of Fluorescent Probes & Dyes
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