FAM amine, 6-isomer

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FAM amine, 6-isomer

FAM amine, 6-isomer | CAS 1313393-44-0

Catalog Number F04-0002
Category Fluorescein FAM
Molecular Formula C27H27N2ClO6
Molecular Weight 510.97
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Product Introduction

FAM amine, 6-isomer is a remarkably versatile and indispensable fluorescent dye employed extensively in the biomedical industry, primarily serves the purpose of effectively and efficiently labeling nucleotides, proteins, and antibodies. Its vast range of applications spans cutting-edge techniques like fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) – essential tools pivotal to the comprehensive study of gene expression and protein localization.

  • Chemical Information

  • Product Specification

  • Computed Properties

  • Patents

Related CAS 2183440-42-6 (hydrochloride)
Synonyms N-(6-Aminohexyl)-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamide
Purity NMR 1H, HPLC-MS (95%)
IUPAC Name N-(6-aminohexyl)-3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxamide
Canonical SMILES C1=CC2=C(C=C1C(=O)NCCCCCCN)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O
InChI InChI=1S/C27H26N2O6/c28-11-3-1-2-4-12-29-25(32)16-5-8-19-22(13-16)27(35-26(19)33)20-9-6-17(30)14-23(20)34-24-15-18(31)7-10-21(24)27/h5-10,13-15,30-31H,1-4,11-12,28H2,(H,29,32)
InChIKey YEKKULZAUQTCSI-UHFFFAOYSA-N
Solubility good in methanol, DMSO, DMF
Appearance yellow solid
ε, L⋅mol-1⋅cm-1 80000
Fluorescence Quantum Yield 0.93
Excitation 490
Emission 513
Storage 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
XLogP3 3.2
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 7
Exact Mass 474.17908655 g/mol
Monoisotopic Mass 474.17908655 g/mol
Topological Polar Surface Area 131Ų
Heavy Atom Count 35
Formal Charge 0
Complexity 751
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Publication Number Title Priority Date
US-2019331688-A1 Screening methods for parp modulators 2018-04-30
WO-2019212946-A1 Screening methods for parp modulators 2018-04-30
US-11293927-B2 Screening methods for PARP modulators 2018-04-30
US-2022206008-A1 Screening methods for parp modulators 2018-04-30
US-6320041-B1 Pre-activated carbonyl linkers for the modification of oligonucleotides 2001-04-13

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