FAM amine, 6-isomer | 1313393-44-0

Catalog Number	F04-0002
Category	Fluorescein FAM
Molecular Formula	C27H27N2ClO6
Molecular Weight	510.97

Catalog Number	Size	Price	Quantity
F04-0002	--	$--

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Product Introduction

FAM amine, 6-isomer is a remarkably versatile and indispensable fluorescent dye employed extensively in the biomedical industry, primarily serves the purpose of effectively and efficiently labeling nucleotides, proteins, and antibodies. Its vast range of applications spans cutting-edge techniques like fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) – essential tools pivotal to the comprehensive study of gene expression and protein localization.

Chemical Information
Product Specification

Related CAS	2183440-42-6 (hydrochloride)
Synonyms	N-(6-Aminohexyl)-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamide
Purity	NMR 1H, HPLC-MS (95%)
IUPAC Name	N-(6-aminohexyl)-3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxamide
Canonical SMILES	C1=CC2=C(C=C1C(=O)NCCCCCCN)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O
InChI	InChI=1S/C27H26N2O6/c28-11-3-1-2-4-12-29-25(32)16-5-8-19-22(13-16)27(35-26(19)33)20-9-6-17(30)14-23(20)34-24-15-18(31)7-10-21(24)27/h5-10,13-15,30-31H,1-4,11-12,28H2,(H,29,32)
InChI Key	YEKKULZAUQTCSI-UHFFFAOYSA-N
Solubility	good in methanol, DMSO, DMF
Appearance	yellow solid

ε, L⋅mol-1⋅cm-1	80000
Fluorescence Quantum Yield	0.93
Excitation	490
Emission	513
Storage	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Computed Properties
XLogP3	3.2
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Exact Mass	474.17908655 g/mol
Monoisotopic Mass	474.17908655 g/mol
Topological Polar Surface Area	131Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	751
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Patents

Publication Number	Title	Priority Date
US-2019331688-A1	Screening methods for parp modulators	2018-04-30
WO-2019212946-A1	Screening methods for parp modulators	2018-04-30
US-11293927-B2	Screening methods for PARP modulators	2018-04-30
US-2022206008-A1	Screening methods for parp modulators	2018-04-30
US-6320041-B1	Pre-activated carbonyl linkers for the modification of oligonucleotides	2001-04-13