
Singlet Oxygen Sensor Green | CAS 865777-57-7
| Catalog Number | A03-0016 |
| Category | NO & ROS Probes |
| Molecular Formula | C6H11N3O3 |
| Molecular Weight | 601.01 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Singlet Oxygen Sensor Green is a fluorogenic probe for detecting singlet oxygen in aqueous solutions.
Chemical Information
Application
Chemical Information
| Synonyms | SOSG; Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic acid, 2'-chloro-3',6'-dihydroxy-7'-(10-methyl-9-anthracenyl)-3-oxo- (9CI, ACI) |
| Solubility | Soluble in Methanol |
| Appearance | Brown Powder |
Application
Singlet Oxygen Sensor Green is a fluorescence probe designed to report singlet oxygen generation in chemical, photochemical, and biological research workflows. The probe's fluorescence response enables monitoring of oxidative stress pathways and reactive oxygen species production in systems where singlet oxygen is the relevant oxidant, supporting mechanistic studies and formulation screening. Its use is common in light-driven chemistry, photodynamic research tool development, and materials stability evaluation where singlet oxygen is expected to form.
1. Photochemical Singlet Oxygen Monitoring
Singlet Oxygen Sensor Green is frequently used in photochemistry and photophysical studies to quantify singlet oxygen formation during irradiation experiments. Researchers apply it to compare photosensitizers, light doses, and oxygenation conditions by tracking fluorescence intensity changes as singlet oxygen is generated in solution or in heterogeneous media. This makes the probe a practical readout tool for screening photoactive additives and evaluating how formulation components influence oxidative reactivity under illumination.
2. Reactive Oxygen Mechanism Studies
Singlet Oxygen Sensor Green supports chemical biology and mechanistic investigations into oxidative pathways where singlet oxygen is implicated. In cell-free assays and controlled biological-mimicking environments, it helps researchers distinguish singlet oxygen-driven effects from other oxidative species by using fluorescence readout as a direct indicator of singlet oxygen presence. Laboratories also use the probe to evaluate how scavengers, quenchers, or radical inhibitors alter the oxidative outcome in light-exposed systems.
3. Materials Photooxidation Screening
Singlet Oxygen Sensor Green is used in biomaterials science and coatings research to assess photooxidative degradation risk associated with singlet oxygen. Researchers incorporate the probe into polymer films, hydrogels, or surface-contact test setups to monitor oxidative stress under light exposure, providing a fluorescence-based indicator of whether photoinduced singlet oxygen formation occurs. This workflow is commonly applied during materials development to guide selection of stabilizers and to compare light-aging behavior across candidate formulations.
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