Propargyl-PEG4-O-C1-NHS ester | 1161883-51-7
Catalog Number | R01-0222 |
Category | Alkynes |
Molecular Formula | C17H25NO9 |
Molecular Weight | 387.38 |
Catalog Number | Size | Price | Quantity |
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R01-0222 | -- | $-- |
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Product Introduction
Propargyl-PEG4-O-C1-NHS ester is a PEG linker containing a propargyl group and an NHS group. It is amine-reactive, thus, useful for derivatizing biomolecules with an amine group. The propargyl group reacts with azides via copper-catalyzed azide-alkyne Click Chemistry to form a stable triazole bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Chemical Information |
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Synonyms | Propargyl-PEG5-CH2CO2-NHS; 2,5-Dioxopyrrolidin-1-yl 3,6,9,12,15-pentaoxaoctadec-17-ynoate; 3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester; Propargyl-PEG4-CH2COONHS; Propargyl-PEG5-CH2COO-NHS ester; Propargyl-PEG5-CH2COOH NHS Ester; 1-(3,6,9,12,15-Pentaoxaoctadec-17-ynoyloxy)-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(1-oxo-3,6,9,12,15-pentaoxaoctadec-17-yn-1-yl)oxy]- |
Purity | ≥95% |
IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]acetate |
Canonical SMILES | C#CCOCCOCCOCCOCCOCC(=O)ON1C(=O)CCC1=O |
InChI | InChI=1S/C17H25NO9/c1-2-5-22-6-7-23-8-9-24-10-11-25-12-13-26-14-17(21)27-18-15(19)3-4-16(18)20/h1H,3-14H2 |
InChI Key | BNRYRRHZTIDZOR-UHFFFAOYSA-N |
Solubility | Soluble in DCM, DMF, DMSO |
Density | 1.3±0.1 g/cm3 |
Appearance | Pale Yellow Oily Matter |
Boiling Point | 486.2±55.0°C at 760 mmHg |
- Product Specification
Storage | Store at 2-8°C |
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