Propargyl-PEG4-acid | 1415800-32-6

Name: Propargyl-PEG4-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Product Introduction

Propargyl-PEG4-acid is a polyethylene glycol (PEG)-based PROTAC linker. Propargyl-PEG4-acid can be used in the synthesis of a series of PROTACs.

Chemical Information
Synonyms	4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid; Propyne-PEG3-CH2CH2COOH; Alkyne-PEG4-COOH; Propargyl-PEG4-COOH; Alkyne-PEG4-acid; Propargyl-PEG3-CH2CH2COOH; 4,7,10,13-tetraoxahexadec-15-ynoic acid; Tetraoxahexadec-15-yn-1-oic acid
Purity	>97%
IUPAC Name	3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid
Canonical SMILES	C#CCOCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C12H20O6/c1-2-4-15-6-8-17-10-11-18-9-7-16-5-3-12(13)14/h1H,3-11H2,(H,13,14)
InChI Key	WMBXAUWIPBFEOK-UHFFFAOYSA-N
Solubility	Soluble in DCM, DMF, DMSO, Water
Density	1.129±0.06 g/cm3 (Predicted)
Appearance	Pale Yellow or Colorless Oily Matter
Boiling Point	388.0±37.0 °C at 760 mmHg

Storage	Store at 2-8°C
Signal	Warning
GHS Hazard Statements	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Computed Properties
XLogP3	-0.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	13
Exact Mass	260.12598835 g/mol
Monoisotopic Mass	260.12598835 g/mol
Topological Polar Surface Area	74.2Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	244
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Publication Number	Title	Priority Date
WO-2022272307-A1	Bifunctional folate receptor binding compounds	2021-06-24
WO-2022150721-A1	Bifunctional folate receptor binding compounds	2021-01-08
WO-2022133281-A1	Compositions and methods for the treatment of human immunodeficiency virus	2020-12-17
WO-2021050612-A1	Compositions and methods for the treatment of respiratory syncytial virus	2019-09-09
CA-3153626-A1	Compositions and methods for the treatment of respiratory syncytial virus	2019-09-09

Applications of Fluorescent Probes & Dyes

Laser Dye

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