Propargyl-PEG3-O-C1-NHS ester

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Propargyl-PEG3-O-C1-NHS ester

Propargyl-PEG3-O-C1-NHS ester | 2144777-76-2

Catalog Number R01-0223
Category Alkynes
Molecular Formula C15H21NO8
Molecular Weight 343.33
Catalog Number Size Price Quantity
R01-0223 -- $--

Product Introduction

Propargyl-PEG3-O-C1-NHS ester is a PEG linker containing a propargyl group and an NHS group. It is amine-reactive, thus, useful for derivatizing biomolecules with an amine group. The propargyl group reacts with azides via copper-catalyzed azide-alkyne Click Chemistry to form a stable triazole bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Chemical Information

Synonyms Propargyl-PEG4-CH2COO-NHS ester; 2,5-Dioxopyrrolidin-1-yl 3,6,9,12-tetraoxapentadec-14-ynoate; Propargyl-PEG4-CH2CO2-NHS; 3,6,9,12-Tetraoxapentadec-14-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester; Propargyl-PEG3-CH2COONHS; 1-(3,6,9,12-Tetraoxapentadec-14-ynoyloxy)-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[(1-oxo-3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy]-
Purity ≥95%
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]acetate
Canonical SMILES C#CCOCCOCCOCCOCC(=O)ON1C(=O)CCC1=O
InChI InChI=1S/C15H21NO8/c1-2-5-20-6-7-21-8-9-22-10-11-23-12-15(19)24-16-13(17)3-4-14(16)18/h1H,3-12H2
InChI Key GYEPTYINFCZLBX-UHFFFAOYSA-N
Solubility Soluble in DCM, DMF, DMSO
Density 1.3±0.1 g/cm3
Boiling Point 451.3±55.0°C at 760 mmHg
  • Product Specification
Storage Store at 2-8°C
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