Mal-PEG2-bis-PEG2-BCN (exo)

Product Introduction

Mal-PEG2-bis-PEG2-BCN (exo) is a heterobifunctional reagent that integrates maleimide and bicyclononyne (BCN) moieties, facilitating orthogonal conjugation strategies in bioconjugation and click chemistry applications. The maleimide group provides selective reactivity towards thiol-containing biomolecules, enabling site-specific conjugation under mild conditions, while the BCN moiety participates in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions, allowing for copper-free click chemistry. The incorporation of PEG spacers enhances solubility and flexibility, making this reagent suitable for linking biomolecules, modifying surfaces, and constructing complex macromolecular assemblies.