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APN-PEG4-BCN(exo)
| Catalog Number | R16-0063 |
| Category | BCN Reagents |
| Molecular Formula | C31H39N3O7 |
| Molecular Weight | 565.66 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
APN-PEG4-BCN(exo) is a synthetic reagent that contains a bicyclononyne (BCN) moiety, which is known for its ability to participate in strain-promoted azide-alkyne cycloaddition reactions. The inclusion of a PEG4 linker enhances its solubility and flexibility, facilitating its integration into various bioconjugation and surface modification protocols. This compound is commonly used in bioorthogonal chemistry for the selective tagging and modification of biomolecules without interfering with natural biological processes.
Chemical Information
Product Specification
Application
Chemical Information
| Purity | >95% |
| Solubility | DCM, THF, Acetonitrile, DMF and DMSO |
| Appearance | Oil |
Product Specification
| Storage | -20 °C |
Application
APN-PEG4-BCN(exo), a specialized ligand with multifaceted applications in bioscience and biotechnology, showcases its versatility in four key applications:
Drug Delivery: Redefining targeted drug delivery, APN-PEG4-BCN(exo) elevates the precision of therapeutic interventions by facilitating site-specific delivery to afflicted tissues. By conjugating it with drugs or nanoparticles, treatment efficacy is amplified while mitigating adverse effects. This groundbreaking approach, particularly pivotal in the realm of cancer therapy, ensures meticulous targeting to eradicate tumor cells while preserving the integrity of healthy tissues.
Molecular Imaging: Spearheading a revolution in molecular imaging, APN-PEG4-BCN(exo) propels the evolution of cutting-edge diagnostic tools for real-time visualization of intricate biological processes. Coupled with imaging agents like fluorescent dyes or radioisotopes, it provides localized contrast in modalities such as MRI, PET, or fluorescence microscopy. Early detection of diseases through advanced imaging techniques enhances diagnostic precision and significantly improves patient outcomes.
Bioconjugation Chemistry: Positioned at the vanguard of bioconjugation chemistry, APN-PEG4-BCN(exo) emerges as a pivotal facilitator in attaching biomolecules to a diverse array of carriers and surfaces. Its bioorthogonal reactivity enables selective and efficient coupling of proteins, antibodies, or other biological entities without compromising their inherent biological functions. This unique capability is foundational in crafting functionalized biomaterials, biosensors, and therapeutic agents with unparalleled precision.
Tissue Engineering: Enabling pioneering advancements in tissue engineering, APN-PEG4-BCN(exo) enriches scaffolds and biomaterials with bioactive molecules, fostering enhanced cell attachment, proliferation, and differentiation. By integrating this ligand, processes of tissue regeneration and repair are stimulated, vital for the development of cutting-edge biomaterials tailored for applications in wound healing, bone regeneration, and various forms of regenerative medicine.
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