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Mal-PEG2-bis-PEG3-BCN (exo)
| Catalog Number | R16-0028 |
| Category | BCN Reagents |
| Molecular Formula | C61H95N7O20 |
| Molecular Weight | 1246.44 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
A heterotrifunctional linker containing two BCN moieties for click chemistry and a maleimide group
Chemical Information
Product Specification
Application
| Purity | >90% |
| Solubility | DCM, THF, acetonitrile, DMF and DMSO |
| Appearance | Oil |
| Storage | -80 °C |
Mal-PEG2-bis-PEG3-BCN (exo) is a bifunctional PEGylation reagent used extensively in bioconjugation and drug delivery systems. Here are some key applications of Mal-PEG2-bis-PEG3-BCN (exo):
Drug Delivery Systems: Mal-PEG2-bis-PEG3-BCN (exo) is used to modify therapeutic molecules, enhancing their solubility, stability, and bioavailability. By conjugating drugs with this reagent, it is possible to improve pharmacokinetics and reduce immunogenicity, leading to more effective and safer treatments. This conjugation strategy is especially useful for developing next-generation biotherapeutics.
Bioconjugation for Imaging: This reagent is valuable in the preparation of bioconjugates for imaging applications, such as in the conjugation of imaging agents to antibodies or other targeting molecules. The enhanced stability and solubility provided by Mal-PEG2-bis-PEG3-BCN (exo) ensure clear, accurate imaging results. This improves diagnostics and allows for precise tracking of biological processes in vivo.
Protein Engineering: Mal-PEG2-bis-PEG3-BCN (exo) is used in protein engineering to create site-specific modifications. By attaching this reagent to proteins, researchers can tailor protein functions and interactions, facilitating studies on protein structure and activity. This is critical for the development of novel enzymes, biocatalysts, and therapeutics.
Targeted Therapy: The bifunctional nature of Mal-PEG2-bis-PEG3-BCN (exo) makes it an ideal tool for targeted therapy design. By conjugating therapeutic agents with targeting moieties, such as antibodies or peptides, it allows for precise delivery of drugs to specific cells or tissues. This enhances the efficacy of treatments while minimizing off-target effects and side effects.
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