ICG-COOH

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ICG-COOH

ICG-COOH | 181934-09-8

Catalog Number F02-0133
Category Cyanine7.5
Molecular Formula C45H50N2O5S
Molecular Weight 730.96
Catalog Number Size Price Quantity
F02-0133 -- $--

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Product Introduction

ICG-COOH (Indocyanine Green Carboxylic Acid) is a derivative of indocyanine green (ICG), a fluorescent dye widely used in medical imaging, particularly in near-infrared (NIR) imaging techniques. The addition of a carboxylic acid group (-COOH) to ICG enhances its ability to be conjugated to biomolecules, such as antibodies or peptides, making it more versatile for targeted imaging applications. ICG-COOH retains the strong NIR fluorescence properties of ICG, making it useful for in vivo imaging, surgical guidance, and photothermal therapy, where it provides high tissue penetration and low background interference due to the NIR wavelength.

  • Chemical Information
  • Product Specification
Synonyms 1H-Benz[e]indolium, 2-[7-[3-(5-carboxypentyl)-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt; Cy7.5 Acid(mono SO3); 4-(2-(7-(3-(5-Carboxypentyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)hepta-1,3,5-trien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate; ICG-carboxylic acid; mono-sulfo-cy7.5 COOH; ICG-Acid
Purity ≥95%
IUPAC Name 4-[2-[7-[3-(5-carboxypentyl)-1,1-dimethylbenzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate
Canonical SMILES CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCCC(=O)O)C=CC=CC=CC=C4C(C5=C(N4CCCCS(=O)(=O)[O-])C=CC6=CC=CC=C65)(C)C)C
InChI InChI=1S/C45H50N2O5S/c1-44(2)39(46(30-16-8-11-25-41(48)49)37-28-26-33-19-12-14-21-35(33)42(37)44)23-9-6-5-7-10-24-40-45(3,4)43-36-22-15-13-20-34(36)27-29-38(43)47(40)31-17-18-32-53(50,51)52/h5-7,9-10,12-15,19-24,26-29H,8,11,16-18,25,30-32H2,1-4H3,(H-,48,49,50,51,52)
InChI Key HIBVKROMGIHYKL-UHFFFAOYSA-N
Solubility Soluble in Water
Appearance Brown to black solid
Storage Store at -20 °C

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