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ICG-COOH | CAS 181934-09-8
| Catalog Number | F02-0133 |
| Category | Cyanine7.5 |
| Molecular Formula | C45H50N2O5S |
| Molecular Weight | 730.96 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| F02-0133 | -- | -- |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
ICG-COOH (Indocyanine Green Carboxylic Acid) is a derivative of indocyanine green (ICG), a fluorescent dye widely used in medical imaging, particularly in near-infrared (NIR) imaging techniques. The addition of a carboxylic acid group (-COOH) to ICG enhances its ability to be conjugated to biomolecules, such as antibodies or peptides, making it more versatile for targeted imaging applications. ICG-COOH retains the strong NIR fluorescence properties of ICG, making it useful for in vivo imaging, surgical guidance, and photothermal therapy, where it provides high tissue penetration and low background interference due to the NIR wavelength.
Chemical Information
Product Specification
| Synonyms | 1H-Benz[e]indolium, 2-[7-[3-(5-carboxypentyl)-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt; Cy7.5 Acid(mono SO3); 4-(2-(7-(3-(5-Carboxypentyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)hepta-1,3,5-trien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate; ICG-carboxylic acid; mono-sulfo-cy7.5 COOH; ICG-Acid |
| Purity | ≥95% |
| IUPAC Name | 4-[2-[7-[3-(5-carboxypentyl)-1,1-dimethylbenzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate |
| Canonical SMILES | CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCCC(=O)O)C=CC=CC=CC=C4C(C5=C(N4CCCCS(=O)(=O)[O-])C=CC6=CC=CC=C65)(C)C)C |
| InChI | InChI=1S/C45H50N2O5S/c1-44(2)39(46(30-16-8-11-25-41(48)49)37-28-26-33-19-12-14-21-35(33)42(37)44)23-9-6-5-7-10-24-40-45(3,4)43-36-22-15-13-20-34(36)27-29-38(43)47(40)31-17-18-32-53(50,51)52/h5-7,9-10,12-15,19-24,26-29H,8,11,16-18,25,30-32H2,1-4H3,(H-,48,49,50,51,52) |
| InChIKey | HIBVKROMGIHYKL-UHFFFAOYSA-N |
| Solubility | Soluble in Water |
| Appearance | Brown to black solid |
| Storage | Store at -20 °C |
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