Biotin BCN

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Biotin BCN

Biotin BCN

Catalog Number R16-0071
Category BCN Reagents
Molecular Formula C31H50N4O7S
Molecular Weight 622.82
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* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Product Introduction

Biotin BCN is a bioconjugation reagent featuring a biotin moiety conjugated to a bicyclo[6.1.0]nonyne (BCN) functional group. The BCN moiety enables strain-promoted azide-alkyne cycloaddition (SPAAC) without copper catalyst, allowing bioorthogonal conjugation with azide-functionalized molecules under mild, biocompatible conditions. Biotin enables high-affinity binding to streptavidin or avidin, facilitating purification, detection, and immobilization applications.

  • Chemical Information

Chemical Information

Synonyms ((1R,8S,9r)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (15-oxo-19-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-14-azanonadecyl)carbamate; Biotin PEG3 BCN; Biotin TEG BCN
SMILES O=C(OC[C@H]1[C@]2([H])CCC#CCC[C@]12[H])NCCCOCCOCCOCCCNC(CCCC[C@H]3[C@]([H])([C@]([H])(CS3)N4)NC4=O)=O
InChI InChI=1S/C31H50N4O7S/c36-28(12-6-5-11-27-29-26(22-43-27)34-30(37)35-29)32-13-7-15-39-17-19-41-20-18-40-16-8-14-33-31(38)42-21-25-23-9-3-1-2-4-10-24(23)25/h23-27,29H,3-22H2,(H,32,36)(H,33,38)(H2,34,35,37)/t23-,24+,25+,26-,27-,29-/m0/s1
InChIKey BQJUTQDCFBVNTR-MVTMSODMSA-N

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