Alkyne-Trebler Pro Phosphoramidite | CAS 2223630-40-6

Name: Alkyne-Trebler Pro Phosphoramidite
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R10-0040
Category	Alkynes
Molecular Formula	C64H90N3O14P
Molecular Weight	1156.40

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Product Introduction

Alkyne-Trebler Pro Phosphoramidite is a branching reagent used in oligonucleotide synthesis. It contains a phosphoramidite moiety with a trebler alkyne structure attached to a hydroxyprolinol linker. The hydroxyprolinol provides a rigid, non-nucleosidic scaffold, while the trebler alkyne architecture facilitates trifurcate branching and subsequent bioorthogonal click chemistry modifications, allowing the synthesis of multivalent or highly functionalized oligonucleotides.

Chemical Information

Chemical Information

Synonyms	(3R,5S)-1-(10,10-Bis((3-(prop-2-yn-1-yloxy)propoxy)methyl)-4,8,12,16-tetraoxanonadec-18-ynoyl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)pyrrolidin-3-yl (2-cyanoethyl) diisopropylphosphoramidite; Alkyne-Trebler Phosphoramidite (hydroxyprolinol)
SMILES	C#CCOCCCOCC(COCCCOCC#C)(COCCCOCC#C)COCCCOCCC(N1C[C@@H](C[C@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)C4=CC=C(C=C4)OC)OP(N(C(C)C)C(C)C)OCCC#N)=O
InChI	InChI=1S/C64H90N3O14P/c1-10-33-71-36-17-40-75-49-63(50-76-41-18-37-72-34-11-2,51-77-42-19-38-73-35-12-3)52-78-43-20-39-74-45-31-62(68)66-47-61(81-82(80-44-16-32-65)67(53(4)5)54(6)7)46-58(66)48-79-64(55-21-14-13-15-22-55,56-23-27-59(69-8)28-24-56)57-25-29-60(70-9)30-26-57/h1-3,13-15,21-30,53-54,58,61H,16-20,31,33-52H2,4-9H3/t58-,61+,82?/m0/s1
InChIKey	MGNDTGJLARYRLB-TXOIWDNHSA-N