Alkyne maleimide

Catalog Number	R02-0006
Category	Alkynes
Molecular Formula	C12H14N2O3
Molecular Weight	234.25

Catalog Number	Size	Price	Quantity
R02-0006	--	$--

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Product Introduction

Alkyne maleimide is a bifunctional linker reagent which allows to attach terminal alkyne to various thiol-containing molecules, such as proteins containing cysteine residues. The alkyne moiety can be then conjugated with various azides via copper-catalyzed Click chemistry reaction.

Chemical Information
Purity	NMR 1H, HPLC-MS (95%)
IUPAC Name	N-[2-(2,5-dioxopyrrol-1-yl)ethyl]hex-5-ynamide
Canonical SMILES	C#CCCCC(=O)NCCN1C(=O)C=CC1=O
InChI	InChI=1S/C12H14N2O3/c1-2-3-4-5-10(15)13-8-9-14-11(16)6-7-12(14)17/h1,6-7H,3-5,8-9H2,(H,13,15)
InChI Key	JFWXHCHRKDOVRJ-UHFFFAOYSA-N
Solubility	good in DMSO, DMF, alcohols, limited in water
Appearance	colorless solid

Computed Properties
XLogP3	-0.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	234.10044231 g/mol
Monoisotopic Mass	234.10044231 g/mol
Topological Polar Surface Area	66.5Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	385
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes