Alkyne-Doubler Phosphoramidite

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Alkyne-Doubler Phosphoramidite

Alkyne-Doubler Phosphoramidite | CAS 2223630-43-9

Catalog Number R10-0038
Category Alkynes
Molecular Formula C53H75N2O11P
Molecular Weight 947.15
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Product Introduction

Alkyne-Doubler Phosphoramidite is a branching reagent used in oligonucleotide synthesis. It contains a phosphoramidite moiety with a doubler alkyne structure, enabling the introduction of multiple alkyne sites within an oligonucleotide chain. The doubler alkyne architecture facilitates dendritic branching and subsequent bioorthogonal click chemistry modifications, allowing the synthesis of multivalent or highly functionalized oligonucleotides.

  • Chemical Information

Chemical Information

Synonyms 3-(3-(3-(Bis(4-methoxyphenyl)(phenyl)methoxy)propoxy)-2,2-bis((3-(prop-2-yn-1-yloxy)propoxy)methyl)propoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite
SMILES N#CCCOP(OCCCOCC(COCCCOCC#C)(COCCCOCC#C)COCCCOC(C1=CC=C(OC)C=C1)(C2=CC=C(OC)C=C2)C3=CC=CC=C3)N(C(C)C)C(C)C
InChI InChI=1S/C53H75N2O11P/c1-9-30-58-32-15-34-60-41-52(42-61-35-16-33-59-31-10-2,44-63-37-18-40-66-67(65-39-14-29-54)55(45(3)4)46(5)6)43-62-36-17-38-64-53(47-19-12-11-13-20-47,48-21-25-50(56-7)26-22-48)49-23-27-51(57-8)28-24-49/h1-2,11-13,19-28,45-46H,14-18,30-44H2,3-8H3
InChIKey YSAQKJSBKQEVFV-UHFFFAOYSA-N
Boiling Point 866.3±65.0 °C at 760 mmHg

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