Inquiry Basket
7-Amino-4-methylcoumarin | 26093-31-2
| Catelog Number | A17-0066 |
| Category | Laser Dyes |
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A17-0066 | -- | $-- |
- Worldwide Delivery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
λ max 354 nm in EthanolSuitable as laser dye and used as a fluorescent labeling reagent for trace determination of enzymes.
Chemical Information |
|
|---|---|
| Synonyms | 7-amino-4-methyl-1-benzopyran-2-one; 7-amino-4-methylchromen-2-one |
| Purity | ≥ 98 % (HPLC) |
| IUPAC Name | 7-amino-4-methylchromen-2-one |
| Canonical SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)N |
| InChI | InChI=1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3 |
| InChI Key | GLNDAGDHSLMOKX-UHFFFAOYSA-N |
| Solubility | Soluble in DMSO, Methanol |
| Density | 1.275 g/cm3 |
| Appearance | Slight yellow powder |
| Boiling Point | 378.3 ℃ at 760 mmHg |
| Melting Point | 223-232 ℃ |
| LogP | 2.26480 |
Product Specification |
|
|---|---|
| Storage | Store at 2-8 ℃ |
| Application | Coumarins are used as laser dyes. Coumarin 120 (Kodak) is the parent compound of the oldest aminocoumarin laser dye, which is Coumarin 311 (Kodak). |
| Signal | Warning |
| GHS Hazard Statements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 175.063328530 g/mol |
| Monoisotopic Mass | 175.063328530 g/mol |
| Topological Polar Surface Area | 52.3Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 260 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22925447 | 2012-09-15 | Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action | Bioorganic & medicinal chemistry |
| 22517611 | 2012-06-04 | Dual-luminophore-labeled gold nanoparticles with completely resolved emission for the simultaneous imaging of MMP-2 and MMP-7 in living cells under single wavelength excitation | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 22402981 | 2012-06-01 | Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes | Apoptosis : an international journal on programmed cell death |
| 22499434 | 2012-06-01 | SERINE proteinase like activity in apolipophorin III from the hemolymph of desert locust, Schistocerca gregaria | Archives of insect biochemistry and physiology |
| 22294421 | 2012-04-01 | Fluorogenic peptide-based substrates for monitoring thrombin activity | ChemMedChem |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-115125232-A | A Sensitive Detection Method of Organophosphorus Pesticide Residues Based on Immobilized Organophosphorus Hydrolase | 2022-06-21 |
| CN-114965454-A | A colorimetric fluorescent dual-mode reagent for on-site detection of nitrite | 2022-05-24 |
| CN-115160204-A | A kind of fibroblast activation protein inhibitor and preparation method and application thereof | 2022-05-13 |
| CN-114869863-A | A kind of multifunctional composite scaffold and its preparation method and application | 2022-05-10 |
| CN-114736193-A | A kind of bedaquiline derivative and preparation method thereof | 2022-04-27 |
Applications of Fluorescent Probes & Dyes
Get More Product Details?
