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2,5-Diphenyloxazole | CAS 92-71-7
| Catalog Number | A17-0124 |
| Category | Laser Dyes |
| Molecular Formula | C15H11NO |
| Molecular Weight | 221.25 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Widely used blue fluor with fast decay time. Perfect for scintillation counting, radiation detection, and fluorescence standards.
Chemical Information
Product Specification
Application
Computed Properties
Literatures
Patents
| Synonyms | Oxazole, 2,5-diphenyl-; DPO; DPO (scintillator); NSC 24856; NSC 49168; PPO; PPO (scintillator); Tritosol |
| Purity | ≥98% |
| IUPAC Name | 2,5-diphenyl-1,3-oxazole |
| Canonical SMILES | C1=CC=C(C=C1)C2=CN=C(O2)C3=CC=CC=C3 |
| InChI | InChI=1S/C15H11NO/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H |
| InChIKey | CNRNYORZJGVOSY-UHFFFAOYSA-N |
| Solubility | Soluble in Methanol |
| Density | 1.128±0.06 g/cm3 |
| Appearance | White powder |
| Boiling Point | 360°C |
| Melting Point | 74°C |
| Vapor Pressure | 0.00000465 [mmHg] |
| LogP | 4.00860 |
| Storage | Store at RT |
| Signal | Warning |
| GHSHazardStatements | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H413 (97.73%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] |
| Precautionary Statement Codes | P264, P264+P265, P270, P273, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
2,5-Diphenyloxazole (PPO), an organic compound utilized in scientific research and industrial settings, boasts diverse applications. Here are four key applications of 2,5-Diphenyloxazole presented:
Scintillation Counting: A cornerstone in liquid scintillation counting, 2,5-Diphenyloxazole emerges as a premier scintillator pivotal in quantifying radioactive isotopes. When dissolved in appropriate solvents, PPO exudes light upon encountering beta particles, rendering it indispensable for discerning and measuring radioactive emissions in an array of samples spanning biological, environmental, and chemical domains.
Fluorescence Studies: Renowned for its exceptional fluorescence traits, PPO finds purpose in fluorescence microscopy and spectroscopy. Functioning as a potent fluorescent dye, it tags diverse biological molecules, enabling visualization and quantification under the discerning gaze of a fluorescence microscope. Researchers harness its capabilities to delve into cellular components, protein interactions, and other intricate molecular processes.
Clinical Diagnostics: At the forefront of medical diagnostics, 2,5-Diphenyloxazole plays a pivotal role in crafting diagnostic assays and sensors. Integrated into diagnostic kits, it aids in detecting specific biomolecules through fluorescence or scintillation techniques. This application stands as a linchpin in early disease identification, monitoring therapeutic interventions, and conducting an array of clinical assessments.
Photodegradable Polymers: Spearheading the development of photodegradable polymers, PPO aligns itself with innovative materials that disassemble upon exposure to light. These polymers can be finely tuned for specialized medical and environmental applications, such as controlled drug delivery systems and biodegradable packaging materials. The integration of PPO imbues these groundbreaking materials with the essential photodegradation attributes, propelling them towards novel frontiers.
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 221.084063974 g/mol |
| Monoisotopic Mass | 221.084063974 g/mol |
| Topological Polar Surface Area | 26Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 231 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22739900 | 2012-06-15 | Ultrabroadband femtosecond two-dimensional ultraviolet transient absorption | Optics letters |
| 22333893 | 2012-04-21 | DNA binding and antiproliferative activity toward human carcinoma cells of copper(II) and zinc(II) complexes of a 2,5-diphenyl[1,3,4]oxadiazole derivative | Dalton transactions (Cambridge, England : 2003) |
| 22307066 | 2012-03-14 | A femtosecond fluorescence study of vibrational relaxation and cooling dynamics of UV dyes | Physical chemistry chemical physics : PCCP |
| 22064915 | 2012-01-07 | Application of PARAFAC to a two-component system exhibiting fluorescence resonance energy transfer: from theoretical prediction to experimental validation | The Analyst |
| 22389718 | 2012-01-01 | Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis | PloS one |
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-115028759-A | A laser manufacturing method based on triplet upconversion and its application | 2022-06-28 |
| CN-114891138-A | A pouring method for the preparation of large volume plastic flash | 2022-06-20 |
| CN-114966805-A | A method and application for rapid analysis of radionuclides based on plastic scintillation resin | 2022-06-08 |
| CN-115128659-A | [14C] High-efficiency absorption scintillation fluid | 2022-05-27 |
| CN-114716830-A | A kind of plastic scintillator and its preparation method and application | 2022-04-14 |
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