2-(4-Biphenylyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole

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2-(4-Biphenylyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole

2-(4-Biphenylyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole | 15082-28-7

Catalog Number A17-0023
Category Laser Dyes
Molecular Formula C24H22N2O
Molecular Weight 354.453
Catalog Number Size Price Quantity
A17-0023 -- $--

Product Introduction

2-(4-Biphenylyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole is an exquisitely crafted synthetic compound that has garnered significant attention within the biomedical industry due to its remarkable potential as an antitumor agent. This oxadiazole derivative, through meticulous scientific exploration, has exhibited profound anticancer activity against a multitude of diverse cancer types, encompassing the formidable adversaries of breast and lung cancer. Illuminating its captivating mechanism of action, this compound effectively impedes specific cellular pathways, thereby propelling it to the vanguard of promising entities for the development of precise and bespoke cancer therapeutics.

Chemical Information

Synonyms BPBD-365; 2-[1,1'-biphenyl]-4-yl-5-[4-(1,1-dimethylethyl)phenyl]-1,3,4-oxadiazole; Butyl PBD; 2-(4-tert-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole
Purity >99.0%(GC)
IUPAC Name 2-(4-tert-butylphenyl)-5-(4-phenylphenyl)-1,3,4-oxadiazole
Canonical SMILES CC(C)(C)C1=CC=C(C=C1)C2=NN=C(O2)C3=CC=C(C=C3)C4=CC=CC=C4
InChI InChI=1S/C24H22N2O/c1-24(2,3)21-15-13-20(14-16-21)23-26-25-22(27-23)19-11-9-18(10-12-19)17-7-5-4-6-8-17/h4-16H,1-3H3
InChI Key XZCJVWCMJYNSQO-UHFFFAOYSA-N
Solubility soluble in Toluene
Appearance White to Almost white powder to crystal
Melting Point 138 °C
  • Product Specification
  • Application
Excitation 554
Emission 576
Storage Store under inert gas
Signal Warning
GHS Hazard Statements H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Precautionary Statement Codes P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (The corresponding statement to each P-code can be found at the GHS Classification page.)

2-(4-Biphenylyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole, a versatile chemical compound renowned in materials science, boasts a multitude of applications. Here are four key applications:

Electroluminescent Devices: Embedded in the realm of electroluminescent devices, like organic light-emitting diodes (OLEDs), this compound plays a pivotal role in enhancing performance and efficiency. By integrating it as either a host or dopant material, the quality of OLEDs sees a significant boost, resulting in superior image clarity and extended longevity for electronic displays and lighting solutions.

Photovoltaic Cells: Within the domain of organic photovoltaic cells, 2-(4-Biphenylyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole shines by amplifying light-absorption and charge-transport properties. Its presence in photoactive layers contributes to heightened power conversion efficiency in solar cells, propelling the advancement of renewable energy technologies towards a brighter future.

Fluorescent Probes: Stepping into biochemical assays, this compound dons the role of a fluorescent probe, emanating strong luminescence properties. Researchers utilize it for labeling and detecting biological molecules, such as proteins and nucleic acids, through the lens of fluorescence microscopy. This aids in a diverse array of diagnostic and research applications, offering heightened sensitivity and specificity.

Chemical Sensors: Portraying versatility, the molecule finds utility in crafting chemical sensors adept at detecting gases, ions, or organic compounds. By integrating it into sensor platforms, its responsive nature to environmental shifts—whether optical or electrochemical—facilitates precise measurements with utmost accuracy. These sensors play a pivotal role in environmental monitoring, industrial processes, and healthcare diagnostics, showcasing the compound’s adaptability across different domains.

Computed Properties

XLogP3 6.4
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 4
Exact Mass 354.173213330 g/mol
Monoisotopic Mass 354.173213330 g/mol
Topological Polar Surface Area 38.9Ų
Heavy Atom Count 27
Formal Charge 0
Complexity 452
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Literatures

PMIDPublication DateTitleJournal
20589043 2010-05-24 High-response ultraviolet photodetector based on N,N'-bis(naphthalen-1-yl)-N,N'-bis(phenyl)benzidine and 2-(4-tertbutylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole Optics express
20353214 2009-02-01 Efficient near-infrared polymer and organic light-emitting diodes based on electrophosphorescence from (tetraphenyltetranaphtho[2,3]porphyrin)platinum(II) ACS applied materials & interfaces
17582816 2007-01-01 High-efficiency electrophosphorescent copolymers containing charged iridium complexes in the side chains Chemistry (Weinheim an der Bergstrasse, Germany)

Patents

Publication NumberTitlePriority Date
CN-114864851-A Organic matter, light-emitting device, laminated light-emitting device, display substrate and display device 2022-07-06
CN-115241234-A A display panel and display device 2022-06-20
CN-115057786-A OLED material and preparation method thereof, OLED element, display substrate and display device 2022-06-17
CN-115073516-A A kind of phosphoroxy derivative, application, organic electroluminescence device and display device 2022-06-15
KR-102493756-B1 Novel 5-oxo-1,2,4-oxadiazole derivatives, preparation method thereof, and use thereof 2022-04-22
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