![2,5-dioxopyrrolidin-1-yl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oate](https://resource.bocsci.com/structure/2243565-12-8.gif)
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5-JOE BCN
| Catalog Number | F12-0010 |
| Category | BCN Reagents |
| Molecular Formula | C44H48Cl2N2O13 |
| Molecular Weight | 883.77 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
5-JOE BCN is a fluorescent labeling reagent featuring a 5-carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein (5-JOE) fluorophore conjugated to a bicyclo[6.1.0]nonyne (BCN) functional group. The BCN moiety enables strain-promoted azide-alkyne cycloaddition (SPAAC) without the need for copper catalyst, allowing bioorthogonal labeling of biomolecules under mild, biocompatible conditions. It is used in oligonucleotide modification, live-cell imaging, and bioconjugation applications.
Chemical Information
Chemical Information
| Synonyms | ((1R,8S,9r)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (1-(4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1-oxo-6,9,12-trioxa-2-azapentadecan-15-yl)carbamate; JOE BCN, 5-isomer; 5-JOE PEG3 BCN; 5-JOE TEG BCN |
| SMILES | ClC(C1=C2C3(C4=CC=C(C=C4C(O3)=O)C(NCCCOCCOCCOCCCNC(OC[C@H]5[C@]6([H])CCC#CCC[C@]56[H])=O)=O)C(C=C7OC)=C(O1)C(Cl)=C7O)=C(C(OC)=C2)O |
| InChI | InChI=1S/C44H48Cl2N2O13/c1-54-33-22-31-39(35(45)37(33)49)60-40-32(23-34(55-2)38(50)36(40)46)44(31)30-12-11-25(21-28(30)42(52)61-44)41(51)47-13-7-15-56-17-19-58-20-18-57-16-8-14-48-43(53)59-24-29-26-9-5-3-4-6-10-27(26)29/h11-12,21-23,26-27,29,49-50H,5-10,13-20,24H2,1-2H3,(H,47,51)(H,48,53)/t26-,27+,29+ |
| InChIKey | KJNVORSPKKNTJZ-PAJDZKLWSA-N |
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