5-JOE Alkyne, CHC protected

Name: 5-JOE Alkyne, CHC protected
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	F12-0008
Category	Alkynes
Molecular Formula	C40H37Cl2NO10
Molecular Weight	762.63

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Product Introduction

5-JOE Alkyne, CHC protected is a fluorescent labeling reagent featuring a 5-carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein (5-JOE) fluorophore with cyclohexylcarbonyl (CHC) protecting groups on the phenolic hydroxyl groups, conjugated to an alkyne functional group. The alkyne moiety enables bioorthogonal click chemistry reactions, while the CHC protection enhances stability during synthesis and handling. It is used in oligonucleotide modification, surface functionalization, and bioconjugation applications.

Chemical Information

Chemical Information

Synonyms	JOE alkyne, 5-isomer, CHC protected; 4',5'-Dichloro-2',7'-dimethoxy-3-oxo-5-(prop-2-yn-1-ylcarbamoyl)-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl dicyclohexanecarboxylate
SMILES	O=C(C1=CC=C2C(C(OC23C4=C(OC5=C3C=C(OC)C(OC(C6CCCCC6)=O)=C5Cl)C(Cl)=C(OC(C7CCCCC7)=O)C(OC)=C4)=O)=C1)NCC#C
InChI	InChI=1S/C40H37Cl2NO10/c1-4-17-43-36(44)23-15-16-25-24(18-23)39(47)53-40(25)26-19-28(48-2)34(51-37(45)21-11-7-5-8-12-21)30(41)32(26)50-33-27(40)20-29(49-3)35(31(33)42)52-38(46)22-13-9-6-10-14-22/h1,15-16,18-22H,5-14,17H2,2-3H3,(H,43,44)
InChIKey	AOQWOEZIPKRCSH-UHFFFAOYSA-N