5-Hexynoic acid, 2-amino-, (2S)-

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5-Hexynoic acid, 2-amino-, (2S)-

5-Hexynoic acid, 2-amino-, (2S)- | 98891-36-2

Catalog Number R01-0052
Category Alkynes
Molecular Formula C6H9NO2
Molecular Weight 127.14100
Catalog Number Size Price Quantity
R01-0052 -- $--

Product Introduction

L-Homopropargylglycine is a PROTAC linker, which is composed of alkyl chains. L-Homopropargylglycine can be used to synthesize a range of PROTACs.

Chemical Information

Synonyms L- Homopropargylglycine (HPG) HCl salt
Purity 95%
IUPAC Name (2S)-2-aminohex-5-ynoic acid
Canonical SMILES C#CCCC(C(=O)O)N
InChI InChI=1S/C6H9NO2/c1-2-3-4-5(7)6(8)9/h1,5H,3-4,7H2,(H,8,9)/t5-/m0/s1
InChI Key SCGJGNWMYSYORS-YFKPBYRVSA-N
Solubility In DMSO: 250 mg/mL (1966.34 mM; Need ultrasonic)
In H2O: 125 mg/mL (983.17 mM; Need ultrasonic)
  • Product Specification
  • Application
Storage -20°C, sealed storage, away from moisture; In solvent, -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

5-Hexynoic acid, 2-amino-, (2S)-, also known as S-2-Amino-5-hexynoic acid, is a versatile compound with diverse scientific and industrial applications. Here are four key applications of this compound:

Drug Development: With its intricate structure, S-2-Amino-5-hexynoic acid plays a crucial role in synthesizing pharmaceutical compounds, acting as a pivotal intermediate. This unique compound aids in the creation of innovative molecules with potential therapeutic benefits. Researchers tap into its chemical complexity within medicinal chemistry, paving the way for the discovery and fine-tuning of novel drugs.

Proteomics: In the realm of proteomics research, derivatives of 5-Hexynoic acid find utility in protein labeling and conjugation strategies. These applications empower scientists to delve into the intricate world of protein interactions and dynamics within cellular environments. By employing advanced techniques like imaging and mass spectrometry, labeled proteins can be meticulously tracked and analyzed, shedding light on complex biological processes.

Bioconjugation: The versatility of this compound shines in bioconjugation endeavors, where it is harnessed to link with biomolecules such as proteins or peptides, giving rise to bioconjugates. These specialized compounds lie at the heart of targeted therapies, diagnostic tools, and imaging agents. By merging the inherent properties of 5-Hexynoic acid with biologically active molecules, researchers craft multifunctional compounds tailored for specific applications.

Chemical Synthesis: Within the realm of organic synthesis, S-2-Amino-5-hexynoic acid stands out as a critical building block, especially in the synthesis of complex molecules. Serving as a precursor in diverse chemical reactions, this compound aids chemists in constructing a myriad of intricate structures for both research and industrial purposes. Its reactivity and array of functional groups render it a versatile asset in synthetic chemistry, offering a robust toolset for chemists to wield in their quest for innovation.

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