5-Hexynoic acid, 2-amino-, (2S)- | CAS 98891-36-2

Name: 5-Hexynoic acid, 2-amino-, (2S)-
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R01-0052
Category	Alkynes
Molecular Formula	C6H9NO2
Molecular Weight	127.14100

Inquiry

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Worldwide Delivery
Quality Assurance
24/7 Customer Service

Product Introduction

L-Homopropargylglycine is a PROTAC linker, which is composed of alkyl chains. L-Homopropargylglycine can be used to synthesize a range of PROTACs.

Chemical Information
Product Specification
Application

Synonyms	L- Homopropargylglycine (HPG) HCl salt
Purity	95%
IUPAC Name	(2S)-2-aminohex-5-ynoic acid
Canonical SMILES	C#CCCC(C(=O)O)N
InChI	InChI=1S/C6H9NO2/c1-2-3-4-5(7)6(8)9/h1,5H,3-4,7H2,(H,8,9)/t5-/m0/s1
InChIKey	SCGJGNWMYSYORS-YFKPBYRVSA-N
Solubility	In DMSO: 250 mg/mL (1966.34 mM; Need ultrasonic) In H2O: 125 mg/mL (983.17 mM; Need ultrasonic)

Storage

-20°C, sealed storage, away from moisture; In solvent, -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

5-Hexynoic acid, 2-amino-, (2S)-, also known as S-2-Amino-5-hexynoic acid, is a versatile compound with diverse scientific and industrial applications. Here are four key applications of this compound:

Drug Development: With its intricate structure, S-2-Amino-5-hexynoic acid plays a crucial role in synthesizing pharmaceutical compounds, acting as a pivotal intermediate. This unique compound aids in the creation of innovative molecules with potential therapeutic benefits. Researchers tap into its chemical complexity within medicinal chemistry, paving the way for the discovery and fine-tuning of novel drugs.

Proteomics: In the realm of proteomics research, derivatives of 5-Hexynoic acid find utility in protein labeling and conjugation strategies. These applications empower scientists to delve into the intricate world of protein interactions and dynamics within cellular environments. By employing advanced techniques like imaging and mass spectrometry, labeled proteins can be meticulously tracked and analyzed, shedding light on complex biological processes.

Bioconjugation: The versatility of this compound shines in bioconjugation endeavors, where it is harnessed to link with biomolecules such as proteins or peptides, giving rise to bioconjugates. These specialized compounds lie at the heart of targeted therapies, diagnostic tools, and imaging agents. By merging the inherent properties of 5-Hexynoic acid with biologically active molecules, researchers craft multifunctional compounds tailored for specific applications.

Chemical Synthesis: Within the realm of organic synthesis, S-2-Amino-5-hexynoic acid stands out as a critical building block, especially in the synthesis of complex molecules. Serving as a precursor in diverse chemical reactions, this compound aids chemists in constructing a myriad of intricate structures for both research and industrial purposes. Its reactivity and array of functional groups render it a versatile asset in synthetic chemistry, offering a robust toolset for chemists to wield in their quest for innovation.