5-FAM BCN

Name: 5-FAM BCN
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	F04-0059
Category	BCN Reagents
Molecular Formula	C42H46N2O11
Molecular Weight	754.83

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Product Introduction

5-FAM BCN is a fluorescent labeling reagent featuring a 5-carboxyfluorescein (5-FAM) fluorophore conjugated to a bicyclo[6.1.0]nonyne (BCN) functional group. The BCN moiety enables strain-promoted azide-alkyne cycloaddition (SPAAC) without copper catalyst, allowing bioorthogonal labeling of biomolecules under mild, biocompatible conditions. It is used in oligonucleotide modification, live-cell imaging, and bioconjugation applications.

Chemical Information

Chemical Information

Synonyms	((1R,8S,9r)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (1-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1-oxo-6,9,12-trioxa-2-azapentadecan-15-yl)carbamate; FAM BCN, 5-isomer; 5-FAM PEG3 BCN; 5-FAM TEG BCN
SMILES	O=C(NCCCOCCOCCOCCCNC(OC[C@H]1[C@]2([H])CCC#CCC[C@]12[H])=O)C3=CC=C(C45C(C=C6)=C(OC7=C4C=CC(O)=C7)C=C6O)C(C(O5)=O)=C3
InChI	InChI=1S/C42H46N2O11/c45-28-10-13-35-37(24-28)54-38-25-29(46)11-14-36(38)42(35)34-12-9-27(23-32(34)40(48)55-42)39(47)43-15-5-17-50-19-21-52-22-20-51-18-6-16-44-41(49)53-26-33-30-7-3-1-2-4-8-31(30)33/h9-14,23-25,30-31,33,45-46H,3-8,15-22,26H2,(H,43,47)(H,44,49)/t30-,31+,33+
InChIKey	QEFAOWJVXDILIN-IGOZTWEASA-N