(2-Cyanoethyl) (2,2-bis(ethoxycarbonyl)-3-(4,4'-dimethoxytrityloxy)propyl-1) N,N-diisopropylphosphoramidite

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(2-Cyanoethyl) (2,2-bis(ethoxycarbonyl)-3-(4,4'-dimethoxytrityloxy)propyl-1) N,N-diisopropylphosphoramidite

(2-Cyanoethyl) (2,2-bis(ethoxycarbonyl)-3-(4,4'-dimethoxytrityloxy)propyl-1) N,N-diisopropylphosphoramidite | 171285-25-9

Catalog Number A19-0083
Category DNA Stains
Molecular Formula C39H51N2O9P
Molecular Weight 722.80
Catalog Number Size Price Quantity
A19-0083 -- $--

Product Introduction

N,N-diisopropylphosphoramidite, a catalytic compound, is an essential building block for oligonucleotide synthesis used in various therapeutic domains such as antisense therapy, siRNA, and gene editing. This efficient and highly pure chemical ensures the production of top-quality therapeutic oligonucleotides.

Chemical Information

Synonyms Chemical phosphorylation reagent for oligonucleotide synthesis; Propanedioic acid, [[bis(4-methoxyphenyl)phenylmethoxy]methyl][[[[bis(1-methylethyl)amino] (2-cyanoethoxy)phosphino]oxy]methyl]-, diethyl ester; CPⅡ; CPRII; 2-[(4,4'-Dimethoxytrityloxy)methyl]-2-[[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]methyl]malonic acid diethyl ester; Diethyl {[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}({[(2-cyanoethoxy)(diisopropylamino)phosphino]oxy}methyl)malonate; Chemical Phosphorylation Reagent II (CPR II); 3-(4,4'-dimethoxytrityloxy)-2,2-dicarboxyethyl]propyl(2-cyanoethyl)(N, N-diisopropyl)phosphoramidite
Purity ≥97% by HPLC
IUPAC Name diethyl 2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-2-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]propanedioate
Canonical SMILES CCOC(=O)C(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)(COP(N(C(C)C)C(C)C)OCCC#N)C(=O)OCC
InChI InChI=1S/C39H51N2O9P/c1-9-46-36(42)38(37(43)47-10-2,28-50-51(49-26-14-25-40)41(29(3)4)30(5)6)27-48-39(31-15-12-11-13-16-31,32-17-21-34(44-7)22-18-32)33-19-23-35(45-8)24-20-33/h11-13,15-24,29-30H,9-10,14,26-28H2,1-8H3
InChI Key IEKIULVSVQLVMS-UHFFFAOYSA-N
Appearance Colorless semisolid
Boiling Point 740.0±60.0°C at 760 mmHg
  • Product Specification
Storage Store at -20 °C
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