Nuclear Yellow | 74681-68-8

Nuclear Yellow is a fluorescent dye used in various bioscience applications for staining and visualization purposes. Here are some key applications of Nuclear Yellow:

Cell Nucleus Staining: Nuclear Yellow is commonly used to stain the nuclei of cells in both live and fixed samples. This helps researchers visualize nuclear structures and identify specific cell populations under a fluorescence microscope. The bright yellow fluorescence emitted by the stained nuclei contrasts well with other fluorescent markers, aiding in detailed cellular studies.

Apoptosis Detection: The dye is also employed in apoptosis assays to identify and quantify apoptotic cells. During apoptosis, nuclear condensation and fragmentation occur, which can be effectively visualized using Nuclear Yellow. This makes it a valuable tool for assessing cell viability and the efficacy of anticancer therapies in research.

Chromosome Analysis: In cytogenetics, Nuclear Yellow is used for chromosome staining during metaphase spreads. This application is particularly useful for karyotyping, where researchers can identify chromosomal abnormalities and study genetic disorders. The distinct fluorescence of Nuclear Yellow aids in the clear visualization of chromosomal structures.

Biomedical Imaging: Nuclear Yellow is utilized in advanced imaging techniques, such as confocal microscopy and flow cytometry. By staining nuclei with Nuclear Yellow, scientists can obtain high-resolution images and accurate data on cellular characteristics. This enhances the study of cell cycle dynamics, gene expression, and cellular differentiation in various research fields.