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IR-775 tosylate | 205744-92-9
| Catalog Number | A17-0044 |
| Category | Laser Dyes |
| Molecular Formula | C39H43ClN2O3S |
| Molecular Weight | 655.3 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A17-0044 | -- | $-- |
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Product Introduction
IR-775 tosylate is used as a laser dye and near-infrared dye.
Chemical Information |
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| Synonyms | 2-[2-[2-Chloro-3-[2-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-ethylidene]-1-cyclohexen-1-yl]-ethenyl]-1,3,3-trimethyl-3H-indolium 4-methylbenzenesulfonate |
| Canonical SMILES | CC1=CC=C(C=C1)S(=O)(=O)[O-].CC1(C2=CC=CC=C2[N+](=C1C=CC3=C(C(=CC=C4C(C5=CC=CC=C5N4C)(C)C)CCC3)Cl)C)C |
| InChI | InChI=1S/C32H36ClN2.C7H8O3S/c1-31(2)24-14-7-9-16-26(24)34(5)28(31)20-18-22-12-11-13-23(30(22)33)19-21-29-32(3,4)25-15-8-10-17-27(25)35(29)6;1-6-2-4-7(5-3-6)11(8,9)10/h7-10,14-21H,11-13H2,1-6H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1 |
| InChI Key | YFKQZQGXOIXGEE-UHFFFAOYSA-M |
- Application
IR-775 tosylate, a versatile near-infrared fluorescent dye, plays a pivotal role in diverse scientific and medical domains. Here are four key applications of IR-775 tosylate:
Optical Imaging: Positioned as a crucial element in near-infrared fluorescence imaging, IR-775 tosylate enables the high-resolution visualization of tissues and organs. This capability proves essential in in vivo imaging scenarios, where significant tissue depth and minimal autofluorescence are critical. Researchers utilize this dye to track cellular and molecular dynamics in real-time, unveiling the intricate tapestry of biological processes with exceptional clarity and precision.
Photodynamic Therapy: Beyond its imaging capabilities, IR-775 tosylate plays a central role in photodynamic therapy (PDT), an advanced treatment approach for cancer and other ailments. When stimulated by near-infrared light, this dye triggers the production of reactive oxygen species that target and eliminate specific cells selectively. This precision in cytotoxicity defines it as a potent therapeutic avenue with minimal harm to surrounding healthy tissues, exemplifying precision medicine in action.
Drug Delivery Systems: Within drug delivery systems, IR-775 tosylate emerges as a key player as a tracking agent. By integrating this dye into nanoparticles or other delivery vehicles, researchers can monitor the distribution and release of pharmaceutical agents within the body in real-time. This live imaging capability is pivotal in refining drug delivery tactics, enhancing therapeutic outcomes, and raising the bar for patient care through cutting-edge visualization methods that redefine pharmaceutical innovation boundaries.
Cell Viability Assays: Leveraging the fluorescence properties of IR-775 tosylate, researchers employ this dye in cell viability assays to differentiate between living and deceased cells with exceptional precision. Its unique characteristics enable thorough assessments of cell health and functionality, crucial in screening drug effectiveness and evaluating cytotoxicity in pharmaceutical research and development realms.
Applications of Fluorescent Probes & Dyes
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