Cyanine5.5 hydrazide

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Cyanine5.5 hydrazide

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide
Catalog Number Size Price Quantity
R05-0009 -- $--

Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.

Chemical Information
Catelog Number: R05-0009
Product Name: Cyanine5.5 hydrazide
Molecular Formula: C40H46Cl2N4O
Molecular Weight: 669.73
Purity: NMR 1H, HPLC-MS (95%)
Solubility: practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
Related CAS: 2280971-80-2 (without anion)
Product Specification
Appearance: dark blue powder
ε, L⋅mol-1⋅cm-1: 198000
Fluorescence quantum Yield: 0.2
Storage Conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
Excitation Maximum (nm): 684
Emission Maximum (nm): 710

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