Coumarin 521

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Coumarin 521

Coumarin 521 | 55804-67-6

Catalog Number F06-0008
Category Laser Dyes
Molecular Formula C17H17NO3
Molecular Weight 283.32
Catalog Number Size Price Quantity
F06-0008 -- $--

Product Introduction

Coumarin 521 is a highly versatile compound widely employed in the biomedical sector and plays an indispensable role in the advancement of pharmaceuticals aimed at combating a myriad of ailments including cancer, diabetes, and cardiovascular disorders. Its distinct attributes facilitate meticulous investigations into potential therapeutic targets and mechanisms of action. Serving as a fluorescent probe, Coumarin 521 proves invaluable for disease identification and monitoring, thus garnering substantial significance in the medical fraternity.

Chemical Information

Synonyms Coumarin 334;10-acetyl-2,3,6,7-tetrahydro-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one; Coumarin 337
Canonical SMILES CC(=O)C1=CC2=CC3=C4C(=C2OC1=O)CCCN4CCC3
InChI InChI=1S/C17H17NO3/c1-10(19)14-9-12-8-11-4-2-6-18-7-3-5-13(15(11)18)16(12)21-17(14)20/h8-9H,2-7H2,1H3
InChI Key JBPCDMSEJVCNGV-UHFFFAOYSA-N
  • Product Specification
  • Application
Excitation 445
Emission 475
Storage 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

Coumarin 521, a versatile fluorescent dye, finds wide-ranging utility in diverse scientific domains. Here are four key applications of Coumarin 521:

Cell Imaging: At the forefront of cell biology, Coumarin 521 plays a pivotal role in fluorescence microscopy by illuminating cellular structures. Through cell staining, researchers delve into dynamic processes like cell division and migration, unraveling the intricate tapestry of cellular functions and interactions in real-time.

Flow Cytometry: In the realm of flow cytometry, Coumarin 521 acts as a fluorescent beacon, labeling specific cell subsets for detailed analysis. This facilitates high-throughput examination of cellular characteristics such as size, complexity, and protein expression. Researchers leverage this data for immunophenotyping, cell sorting, and investigating cellular responses to diverse treatments.

Protein Labeling: Delving into the realm of protein dynamics, Coumarin 521 becomes instrumental by binding to proteins and unveiling their localization, interactions, and behaviors within living cells. Tracking these fluorescently labeled proteins sheds light on intricate protein functions and molecular pathways crucial for deciphering disease mechanisms and steering targeted therapy development.

Environmental Sensing: Extending its reach into environmental science, Coumarin 521 emerges as a potent tool for detecting and monitoring contaminants in water and soil. Its unique fluorescence properties respond sensitively to specific chemicals, serving as a beacon for environmental pollution assessment and guiding the formulation of effective remediation strategies.

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