BAPTA-TMFM | 96315-11-6

BAPTA-TMFM, a widely utilized calcium chelator in research, plays a crucial role in studying calcium dynamics within cells. Here are four key applications of BAPTA-TMFM:

Intracellular Calcium Measurement: Delving into live cells, BAPTA-TMFM serves as a vital tool for measuring intracellular calcium concentrations. Through its buffering action on calcium, this chelator enables researchers to meticulously monitor calcium fluctuations without disrupting normal cellular functions. This application is pivotal for unraveling the intricate involvement of calcium in processes such as muscle contraction, neurotransmitter release, and cell signaling.

Cell Viability Studies: In the realm of investigating cell death mechanisms, BAPTA-TMFM emerges as a key player in modulating intracellular calcium levels. By chelating calcium, this compound aids in shedding light on the role of calcium overload in apoptosis and necrosis. Such insights can be instrumental in identifying potential therapeutic targets for conditions marked by uncontrolled cell death, including neurodegenerative diseases.

Signal Transduction Research: At the forefront of exploring calcium-dependent signaling pathways, BAPTA-TMFM stands out as an indispensable tool for researchers. Leveraging this chelator, scientists can decipher the impact of calcium signals on diverse cellular responses, ranging from gene expression to enzyme activation. This intricate understanding of signaling pathways is paramount for the development of drugs capable of modulating cellular signaling in disease contexts.

Electrophysiological Studies: Within the realm of electrophysiological experimentation, BAPTA-TMFM plays a pivotal role in stabilizing the calcium environment of neuronal cells. Through precise control of calcium levels, researchers can delve into the electrophysiological properties of neurons, such as action potential firing and synaptic transmission. This in-depth analysis aids in unraveling the ionic mechanisms underlying neural activity and excitability, advancing our understanding of neuronal function.