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8-Methoxypyrene-1,3,6-trisulfonic acid trisodium salt | CAS 82962-86-5
| Catalog Number | A16-0184 |
| Category | Cell Proliferation Tracer Fluorescent Probes |
| Molecular Formula | C17H9Na3O10S3 |
| Molecular Weight | 538.398 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
This pyrene fluorescent dye provides sharp emission peaks for calibration and sensing in aqueous systems. Order from a fluorescent probe supplier for consistent optical performance in fluorescence assays.
Chemical Information
Application
Computed Properties
Patents
| Synonyms | MPTS; PyBlue Methyl Ether |
| IUPAC Name | trisodium;8-methoxypyrene-1,3,6-trisulfonate |
| Canonical SMILES | COC1=CC(=C2C=CC3=C(C=C(C4=C3C2=C1C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+] |
| InChI | InChI=1S/C17H12O10S3.3Na/c1-27-12-6-13(28(18,19)20)9-4-5-11-15(30(24,25)26)7-14(29(21,22)23)10-3-2-8(12)16(9)17(10)11;;;/h2-7H,1H3,(H,18,19,20)(H,21,22,23)(H,24,25,26);;;/q;3*+1/p-3 |
| InChIKey | GUGNSJAORJLKGP-UHFFFAOYSA-K |
| Appearance | Solid Powder |
Cell Proliferation Studies: 8-Methoxypyrene-1,3,6-trisulfonic acid trisodium salt is widely used as a cell proliferation tracer in various biological research applications. Its fluorescent properties allow researchers to monitor cell division and growth in real-time. By incorporating this probe into cell cultures, scientists can quantify the proliferation rate of different cell types, providing essential insights into cell cycle dynamics. This application is particularly valuable in cancer research, where understanding the proliferation of tumor cells can inform therapeutic strategies and drug development.
Toxicology Assessments: Another critical application of 8-Methoxypyrene-1,3,6-trisulfonic acid trisodium salt is in toxicology assessments. This fluorescent probe is utilized to evaluate the effects of various toxic substances on cell viability and proliferation. By monitoring changes in fluorescence intensity, researchers can determine the cytotoxicity of compounds, allowing for the identification of potential hazards in pharmaceuticals, chemicals, and environmental samples. This application is crucial for risk assessment and regulatory compliance in toxicology studies, enabling safer product development and environmental monitoring.
Investigating Cellular Signaling Pathways: 8-Methoxypyrene-1,3,6-trisulfonic acid trisodium salt is also instrumental in studying cellular signaling pathways. Its ability to serve as a fluorescence-based marker allows researchers to investigate how signaling molecules influence cell proliferation and survival. By using this probe in combination with specific inhibitors or activators of signaling pathways, scientists can delineate the intricate networks that regulate cellular responses to external stimuli. This application is significant in understanding mechanisms underlying various diseases, including cancer and metabolic disorders, thereby aiding in the development of targeted therapies.
In Vivo Imaging: Furthermore, 8-Methoxypyrene-1,3,6-trisulfonic acid trisodium salt is gaining attention in the field of in vivo imaging. Its favorable fluorescence properties make it suitable for tracing cellular processes in live animal models. Researchers can administer this probe to track the migration and proliferation of specific cell populations, providing valuable data on cellular behavior in a physiological context. This application is particularly relevant in regenerative medicine and cancer biology, where monitoring the fate of transplanted or tumor cells in real-time can yield insights into treatment efficacy and disease progression.
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 1 |
| Exact Mass | 537.90509285 g/mol |
| Monoisotopic Mass | 537.90509285 g/mol |
| Topological Polar Surface Area | 206Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 948 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 4 |
| Compound Is Canonicalized | Yes |
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114990047-A | A method for isolation and detection of newborn exosomes | 2022-05-17 |
| CN-114632426-A | Copper single-atom supported film and its preparation method and application | 2022-02-24 |
| CN-114401376-A | Method and device for playing multi-screen video | 2021-12-31 |
| CN-114401193-A | A kind of HLS slicing method and device supporting MPTS | 2021-12-27 |
| CN-114106978-A | Kit and method for simultaneously detecting internal microRNA and surface protein of exosome | 2021-11-22 |
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