Lucifer yellow cadaverine | 149733-79-9
Catalog Number | A16-0078 |
Category | Cell proliferation tracer Fluorescent Probes |
Molecular Formula | C17H17K2N3O8S2 |
Molecular Weight | 533.66 |
Catalog Number | Size | Price | Quantity |
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A16-0078 | -- | $-- |
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Product Introduction
Lucifer yellow cadaverine can be used as a cell tracer.
Chemical Information |
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Synonyms | Dipotassium 6-amino-2-(5-aminopentyl)-1,3-dioxobenzo[de]isoquinoline-5,8-disulfonate; N-(5-Aminopentyl)-4-amino-3,6-disulfo-1,8-naphthalimide dipotassium salt |
IUPAC Name | dipotassium;6-amino-2-(5-aminopentyl)-1,3-dioxobenzo[de]isoquinoline-5,8-disulfonate |
Canonical SMILES | C1=C(C=C2C3=C1C(=O)N(C(=O)C3=CC(=C2N)S(=O)(=O)[O-])CCCCCN)S(=O)(=O)[O-].[K+].[K+] |
InChI | InChI=1S/C17H19N3O8S2.2K/c18-4-2-1-3-5-20-16(21)11-7-9(29(23,24)25)6-10-14(11)12(17(20)22)8-13(15(10)19)30(26,27)28;;/h6-8H,1-5,18-19H2,(H,23,24,25)(H,26,27,28);;/q;2*+1/p-2 |
InChI Key | BCNIPDJYRQVEOI-UHFFFAOYSA-L |
Appearance | Solid Powder |
- Product Specification
- Application
Excitation | 553 |
Emission | 575 |
Lucifer yellow cadaverine, a fluorescent dye widely utilized in biological research, offers diverse applications. Here are four key applications:
Neuronal Tracing: In the realm of neurobiology, Lucifer yellow cadaverine plays a pivotal role in tracing neuronal pathways. Through targeted injection into specific neurons, researchers unveil the intricate web of neuronal connections, allowing for the visualization and mapping of neural networks. This technique is indispensable for unraveling the organization and functionality of the complex nervous system.
Cell Viability Assays: Within the realm of cell biology, Lucifer yellow cadaverine serves as a valuable tool for evaluating cell viability and membrane integrity. By introducing the dye to cell cultures, researchers can distinguish between viable cells that exclude the dye and damaged cells that absorb it. This method is crucial for discerning between living and deceased cells, enabling the assessment of cytotoxic effects of compounds and ensuring the vitality of cultured cells.
Gap Junction Studies: Delving into intercellular communication, Lucifer yellow cadaverine is employed to study gap junction interactions among cells. Capable of traversing intercellular channels, the dye offers a means to quantify the extent and functionality of gap junctional coupling. This research is particularly pertinent for investigations into tissue homeostasis and intercellular signaling mechanisms.
Intracellular Injection: Researchers leverage Lucifer yellow cadaverine for precise microinjection into individual cells, targeting specific structures or compartments within cellular entities. This technique facilitates detailed imaging and analysis of cellular architecture and dynamics, enabling a comprehensive exploration of cellular processes and interactions at a microscopic level.
Computed Properties | |
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Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 10 |
Rotatable Bond Count | 5 |
Exact Mass | 532.9731198 g/mol |
Monoisotopic Mass | 532.9731198 g/mol |
Topological Polar Surface Area | 221Ų |
Heavy Atom Count | 32 |
Formal Charge | 0 |
Complexity | 868 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 3 |
Compound Is Canonicalized | Yes |
Applications of Fluorescent Probes & Dyes
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