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7-Hydroxy-4-methyl-3-coumarinylacetic acid | CAS 5852-10-8
| Catalog Number | A15-0006 |
| Category | pH Indicators |
| Molecular Formula | C12H10O5 |
| Molecular Weight | 234.21 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
7-Hydroxy-4-methylcoumarin-3-acetic acid is an amine-reactive, blue-fluorescent dye used for pH measurement.
Chemical Information
Product Specification
Application
| Synonyms | 2-(7-Hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid |
| Canonical SMILES | CC1=C(C(=O)OC2=C1C=CC(=C2)O)CC(=O)O |
| InChI | InChI=1S/C12H10O5/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4,13H,5H2,1H3,(H,14,15) |
| InChIKey | OOGKDHCQSZAEQI-UHFFFAOYSA-N |
| Appearance | Solid Powder |
| Excitation | 454 |
| Emission | 524 |
7-Hydroxy-4-methyl-3-coumarinylacetic acid, a coumarin derivative, has multiple applications across various fields due to its unique chemical properties, particularly its role as a pH indicator. One primary application is its use in analytical biochemistry for titrations. As a halochromic compound, it can effectively indicate the endpoint of acid-base titrations by changing color. This change results from the compound’s structural response to different pH levels, making it a vital tool for determining the acidity or basicity of solutions in both research and educational laboratory settings. The clear and precise color change enables accurate and efficient measurements, essential for experiments that require rigorous pH control.
In the realm of environmental science, 7-Hydroxy-4-methyl-3-coumarinylacetic acid is utilized for monitoring water quality. Environmental professionals leverage its pH-indicating properties to assess the health of various water bodies. Its ability to visually signal pH changes allows quick on-site testing and monitoring of lakes, rivers, and oceans, helping detect pollution, eutrophication, or acidification events. This application is critical for maintaining ecological balance and ensuring safe water for wildlife and human consumption. Furthermore, using such indicators aids in compliance with environmental regulations and standards aimed at protecting natural resources.
The pharmaceutical industry also benefits from 7-Hydroxy-4-methyl-3-coumarinylacetic acid, especially in drug formulation and testing. The compound’s pH sensitivity is exploited to ensure the stability and efficacy of pharmaceutical products. For instance, certain medications require precise pH conditions to maintain their chemical integrity and bioavailability. By incorporating this pH indicator into the quality control processes, manufacturers can monitor pH fluctuations during production and storage, thus safeguarding the therapeutic properties of the drugs. Additionally, it aids in research for novel drug development where pH stability is a critical parameter.
Another significant application is in clinical diagnostics. 7-Hydroxy-4-methyl-3-coumarinylacetic acid is used in various diagnostic kits to measure the pH of biological fluids such as urine, blood, and saliva. Accurate pH readings are crucial for diagnosing numerous medical conditions, including metabolic imbalances, respiratory issues, and urinary tract infections. Its reliable colorimetric response helps clinicians quickly interpret results and make informed decisions about patient care. The ease of use and rapid response of this pH indicator enhance the efficiency of diagnostic procedures, contributing to improved health outcomes.
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