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5-Carboxytetramethylrhodamine succinimidyl ester | 150810-68-7
| Catalog Number | A19-0011 |
| Category | DNA Stains |
| Molecular Formula | C29H25N3O7 |
| Molecular Weight | 527.53 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A19-0011 | 250 mg | $729 |
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Product Introduction
5-Carboxytetramethylrhodamine succinimidyl ester is an amine-reactive, orange-fluorescent dye used for labeling DNA and RNA. It also has been used to create bioconjugates with peptides, proteins and enzymes.
Chemical Information |
|
|---|---|
| Synonyms | 5-TAMRA SE; 5-TAMRA N-succinimidyl ester; 5-Carboxy-tetramethylrhodamine N-succinimidyl ester |
| IUPAC Name | 2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-(2,5-dioxopyrrolidin-1-yl)oxycarbonylbenzoate |
| Canonical SMILES | CN(C)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](C)C)C=C3O2)C4=C(C=C(C=C4)C(=O)ON5C(=O)CCC5=O)C(=O)[O-] |
| InChI | InChI=1S/C29H25N3O7/c1-30(2)17-6-9-20-23(14-17)38-24-15-18(31(3)4)7-10-21(24)27(20)19-8-5-16(13-22(19)28(35)36)29(37)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3 |
| InChI Key | VWFRSNKRTNUMET-UHFFFAOYSA-N |
| Appearance | Solid Powder |
- Product Specification
| Excitation | 546 nm |
| Emission | 580 nm |
Computed Properties | |
|---|---|
| XLogP3 | 2.6 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 5 |
| Exact Mass | 527.16925015 g/mol |
| Monoisotopic Mass | 527.16925015 g/mol |
| Topological Polar Surface Area | 119Ų |
| Heavy Atom Count | 39 |
| Formal Charge | 0 |
| Complexity | 1140 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 23047524 | 2012-11-21 | A DNA based five-state switch with programmed reversibility | Chemical communications (Cambridge, England) |
| 22364288 | 2012-07-01 | Probing the interaction between fluorophores and DNA nucleotides by fluorescence correlation spectroscopy and fluorescence quenching | Photochemistry and photobiology |
| 22740458 | 2012-07-01 | A comparative study of LED-induced fluorescence and laser-induced fluorescence in SDS-CGE: application to the analysis of antibodies | Electrophoresis |
| 22542927 | 2012-06-01 | Monitoring of proteolytic enzyme activity using phase transition-based peptide arrays | Biosensors & bioelectronics |
| 22560162 | 2012-06-01 | Oligonucleotide-based fluorogenic sensor for simultaneous detection of heavy metal ions | Biosensors & bioelectronics |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022182415-A1 | Himastatin derivatives, and processes of preparation thereof, and uses thereof | 2021-02-24 |
| CN-112876540-A | Application of an affinity peptide in the preparation of anti-coronavirus drugs | 2021-02-09 |
| CN-112876540-B | Application of an affinity peptide in the preparation of anti-coronavirus drugs | 2021-02-09 |
| CN-114686599-A | Quantitative detection method and kit for DNA residue content in host insect cells | 2020-12-30 |
| CN-112322715-A | A nucleic acid sequencing method | 2020-11-17 |
Applications of Fluorescent Probes & Dyes
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