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2',7'-Dichlorofluorescein | 76-54-0
| Catalog Number | A17-0109 |
| Category | Laser Dyes |
| Molecular Formula | C20H10Cl2O5 |
| Molecular Weight | 401.20 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A17-0109 | -- | $-- |
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Product Introduction
2',7'-Dichlorofluorescein can be used in the synthesis of 2',7'-Dichlorodihydrofluorescein, which is a cell-permeable non-fluorescent probe.
Chemical Information |
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|---|---|
| Synonyms | 2',7'-dichloro-3',6'-dihydroxy-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one; 2',7'-Dichlorofluorescein; Fluorescein 27; Fluorescein 548 |
| IUPAC Name | 2',7'-dichloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one |
| Canonical SMILES | C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C=C4OC5=CC(=C(C=C35)Cl)O)O)Cl |
| InChI | InChI=1S/C20H10Cl2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H |
| InChI Key | VFNKZQNIXUFLBC-UHFFFAOYSA-N |
- Product Specification
| Signal | Warning |
| GHS Hazard Statements | H315 (90.91%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| XLogP3 | 4.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 0 |
| Exact Mass | 399.9905288 g/mol |
| Monoisotopic Mass | 399.9905288 g/mol |
| Topological Polar Surface Area | 76Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 585 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 34958783 | 2022-01-15 | Effect of major components of Tripterygium wilfordii Hook. f on the uptake function of organic anion transporting polypeptide 1B1 | Toxicology and applied pharmacology |
| 22910297 | 2012-11-01 | Oxidative effects of nanosecond pulsed electric field exposure in cells and cell-free media | Archives of biochemistry and biophysics |
| 22939937 | 2012-11-01 | Proinflammatory activation of macrophages by bisphenol A-glycidyl-methacrylate involved NFκB activation via PI3K/Akt pathway | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association |
| 22940460 | 2012-11-01 | Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes | Toxicology and applied pharmacology |
| 23022691 | 2012-11-01 | Nuclear targeting terpyridine iron(II) complexes for cellular imaging and remarkable photocytotoxicity | Journal of inorganic biochemistry |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-115177736-A | Tantalum amide nanoparticles with cartilage targeting and catalase activity and preparation method and use | 2022-07-20 |
| CN-115177746-A | Non-viral gene vector-transfected stem cell complex for the treatment of spinal cord injury | 2022-07-12 |
| CN-115068608-A | Phthalocyanine-artesunate oxygen-carrying liposome complex and its application in sonodynamics | 2022-06-22 |
| CN-114989189-A | A compound with aggregation-induced luminescence properties, preparation method and application thereof | 2022-06-06 |
| CN-114874346-A | A kind of lilac mushroom polysaccharide and its preparation method and application | 2022-05-23 |
Applications of Fluorescent Probes & Dyes
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