Zinquin ethyl ester | 181530-09-6

Zinquin ethyl ester, a fluorescent zinc ion indicator commonly utilized in biological research, serves as a versatile tool in various scientific investigations. Here are four key applications of Zinquin ethyl ester:

Intracellular Zinc Imaging: Widely employed for visualizing and quantifying zinc ion concentrations within cells, Zinquin ethyl ester enables researchers to monitor dynamic changes in intracellular zinc levels through fluorescence microscopy. This application plays a pivotal role in unraveling the significance of zinc in diverse cellular processes, such as enzyme functionality and signal transduction dynamics.

Neurobiology: In the realm of neurobiology, Zinquin ethyl ester facilitates the exploration of zinc dynamics within neuronal cells. Zinc signaling is essential for neurotransmission and synaptic plasticity, and this ester allows real-time visualization of zinc distribution in neurons, offering insights into the ramifications of zinc dysregulation in neurodegenerative conditions like Alzheimer’s and Parkinson’s disease.

Oxidative Stress Research: Scientists utilize Zinquin ethyl ester in the investigation of zinc’s involvement in oxidative stress responses and antioxidant defense mechanisms. By tracking zinc ions, researchers can probe how zinc contributes to counteracting oxidative damage and maintaining redox balance. This application holds particular significance in elucidating the pathophysiology of diseases associated with oxidative stress, such as cancer and cardiovascular disorders.

Pharmacological Screening: Playing a crucial role in pharmacological studies, Zinquin ethyl ester aids in the identification of compounds that modulate intracellular zinc levels. Through high-throughput screening assays incorporating this ester, scientists can pinpoint potential drugs that either chelate or release zinc ions, paving the way for the development of therapeutic agents targeting zinc homeostasis in a spectrum of diseases.