10-(3-Sulfopropyl)acridinium betaine | CAS 83907-41-9

Catalog Number	A14-0129
Category	Calcium, Chloride and Other indicators
Molecular Formula	C16H15NO3S
Molecular Weight	301.36

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Product Introduction

10-(3-Sulfopropyl)acridinium betaine is a zwitterionic fluorescent dye characterized by its acridinium-based chromophore, which exhibits notable solvatochromic behavior. This compound features a sulfopropyl group that enhances its water solubility and facilitates its incorporation into aqueous biological systems for fluorescence imaging and labeling applications. It is frequently utilized in studies involving fluorescence resonance energy transfer (FRET) due to its distinct excitation and emission properties, serving as a reliable component in the development of sensitive biosensors and molecular probes.

Chemical Information
Application

Chemical Information

Synonyms	SPA
SMILES	C1=CC=C2C(=C1)C=C3C=CC=CC3=[N+]2CCCS(=O)(=O)[O-]
InChI	InChI=1S/C16H15NO3S/c18-21(19,20)11-5-10-17-15-8-3-1-6-13(15)12-14-7-2-4-9-16(14)17/h1-4,6-9,12H,5,10-11H2
InChIKey	SMKBSSHVLHIPLU-UHFFFAOYSA-N
Appearance	Solid Powder

Application

The compound known as 10-(3-Sulfopropyl)acridinium betaine is a derivative of acridinium, an aromatic organic compound comprised of a tricyclic structure. This amphoteric zwitterion, possessing a sulfonate group and an acridinium moiety, exhibits photophysical properties that make it a versatile compound in various scientific applications. The structure of (3-Sulfopropyl)acridinium involves a positively charged nitrogen in the acridinium core and a negatively charged sulfonate group anchored on a propyl chain, attributing unique solubility and reactive characteristics to the compound.

One of the primary applications of 10-(3-Sulfopropyl)acridinium betaine is in the field of chemiluminescence. This compound acts as a luminescent probe in biochemical assays, including immunoassays and enzyme assays. Upon oxidation, (3-Sulfopropyl)acridinium betaine emits light, a property exploited for detecting and quantifying biological molecules with high sensitivity and specificity. This makes it invaluable in clinical diagnostics and research where precise measurement of biomarkers is crucial.

Another significant application of 10-(3-Sulfopropyl)acridinium betaine is in imaging technologies. Due to its ability to produce luminescence, it serves as an imaging agent in analytical chemistry and medical diagnostics. Its incorporation in imaging protocols allows for enhanced visualization of biological processes and structures, providing critical information that aids in both experimental and clinical settings. The bright luminescence aids in the accurate detection of target analytes in complex biological matrices, making research outcomes more reliable and accurate.

Additionally, the compound finds utility in the field of material sciences. Researchers exploit its photophysical attributes to develop luminescent materials for various technological applications. These include the creation of LEDs, displays, and sensors where controlled emission properties are essential. The stability and versatility of (3-Sulfopropyl)acridinium betaine contribute to its integration into novel materials with applications that span across optoelectronic devices to environmental sensors.

Lastly, 10-(3-Sulfopropyl)acridinium betaine plays a role in environmental monitoring. Its luminescent response to oxidative states makes it a tool for detecting the presence of certain environmental pollutants. By tracking luminescence changes, scientists can infer the presence and concentration of reactive oxygen species or other oxidative compounds in environmental samples. This application supports efforts in monitoring pollution and studying environmental health, contributing to the understanding and mitigation of industrial impacts on ecosystems.