Z-LLE-AMC

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Z-LLE-AMC

Z-LLE-AMC | 348086-66-8

Catelog Number A18-0062
Category Fluorescent Enzyme Substrates
Molecular Formula C35H44N4O9
Molecular Weight 664.76
Catalog Number Size Price Quantity
A18-0062 -- $--

Product Introduction

Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. AMC (7-amino-4-methylcoumarin) is released to quantify the caspase-like hydrolase activity.

Chemical Information

Synonyms Proteasome Substrate III, Fluorogenic
Purity >95%
IUPAC Name (4S)-4-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]-5-[(4-methyl-2-oxochromen-7-yl)amino]-5-oxopentanoic acid
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC3=CC=CC=C3
InChI InChI=1S/C35H44N4O9/c1-20(2)15-27(38-34(45)28(16-21(3)4)39-35(46)47-19-23-9-7-6-8-10-23)33(44)37-26(13-14-30(40)41)32(43)36-24-11-12-25-22(5)17-31(42)48-29(25)18-24/h6-12,17-18,20-21,26-28H,13-16,19H2,1-5H3,(H,36,43)(H,37,44)(H,38,45)(H,39,46)(H,40,41)/t26-,27-,28-/m0/s1
InChI Key FOYHOBVZPWIGJM-KCHLEUMXSA-N
Solubility Soluble in DMSO
Density 1.253±0.06 g/cm3(Predicted)
Appearance Solid Lyophilized Powder
Boiling Point 967.8±65.0°C at 760 mmHg

Product Specification

Excitation 340-360 nm
Emission 440-460 nm
Storage Store at -20°C
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