Z-LLE-AMC | 348086-66-8
Catelog Number | A18-0062 |
Category | Fluorescent Enzyme Substrates |
Molecular Formula | C35H44N4O9 |
Molecular Weight | 664.76 |
Catalog Number | Size | Price | Quantity |
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A18-0062 | -- | $-- |
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Product Introduction
Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. AMC (7-amino-4-methylcoumarin) is released to quantify the caspase-like hydrolase activity.
Chemical Information |
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Synonyms | Proteasome Substrate III, Fluorogenic |
Purity | >95% |
IUPAC Name | (4S)-4-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]-5-[(4-methyl-2-oxochromen-7-yl)amino]-5-oxopentanoic acid |
Canonical SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC3=CC=CC=C3 |
InChI | InChI=1S/C35H44N4O9/c1-20(2)15-27(38-34(45)28(16-21(3)4)39-35(46)47-19-23-9-7-6-8-10-23)33(44)37-26(13-14-30(40)41)32(43)36-24-11-12-25-22(5)17-31(42)48-29(25)18-24/h6-12,17-18,20-21,26-28H,13-16,19H2,1-5H3,(H,36,43)(H,37,44)(H,38,45)(H,39,46)(H,40,41)/t26-,27-,28-/m0/s1 |
InChI Key | FOYHOBVZPWIGJM-KCHLEUMXSA-N |
Solubility | Soluble in DMSO |
Density | 1.253±0.06 g/cm3(Predicted) |
Appearance | Solid Lyophilized Powder |
Boiling Point | 967.8±65.0°C at 760 mmHg |
Product Specification |
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Excitation | 340-360 nm |
Emission | 440-460 nm |
Storage | Store at -20°C |
Applications of Fluorescent Probes & Dyes
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