![{[Name]}](/probes/images/structure-default.jpg?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/active-mono-sulfone-peg9-dbco.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/bis-dbco-peg4.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/2182601-72-3.gif?v=2025011501)
Inquiry Basket
TCO-PEG24-DBCO
| Catalog Number | R01-0338 |
| Category | Cycloalkyne Dyes (DBCO) |
| Molecular Formula | C78H129N3O28 |
| Molecular Weight | 1556.9 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R01-0338 | -- | -- |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
TCO-PEG24-DBCO is a highly complex multifunctional linker that is widely used in biomedicine and bioconjugation fields. It facilitates the precise and optimized combination of therapeutics with molecular targets, revolutionizing targeted therapy for a variety of diseases, including malignancies, infectious diseases, and autoimmune disorders. The inherent purity and stability of TCO-PEG24-DBCO also have broad applications in drug delivery systems and molecular imaging.
Chemical Information
Product Specification
Application
Computed Properties
| IUPAC Name | [(4E)-cyclooct-4-en-1-yl] N-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate |
| Canonical SMILES | C1CC=CCCC(C1)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42 |
| InChI | InChI=1S/C78H129N3O28/c82-76(79-20-18-77(83)81-70-73-12-7-6-10-71(73)16-17-72-11-8-9-15-75(72)81)19-22-85-24-26-87-28-30-89-32-34-91-36-38-93-40-42-95-44-46-97-48-50-99-52-54-101-56-58-103-60-62-105-64-66-107-68-69-108-67-65-106-63-61-104-59-57-102-55-53-100-51-49-98-47-45-96-43-41-94-39-37-92-35-33-90-31-29-88-27-25-86-23-21-80-78(84)109-74-13-4-2-1-3-5-14-74/h1-2,6-12,15,74H,3-5,13-14,18-70H2,(H,79,82)(H,80,84)/b2-1+ |
| InChIKey | ROGUNNCGVPWZMG-OWOJBTEDSA-N |
| Storage | -20 °C |
TCO-PEG24-DBCO is a bifunctional linker molecule used in various bioconjugation applications, linking biomolecules through click chemistry reactions. Here are some key applications of TCO-PEG24-DBCO:
Bioconjugation: TCO-PEG24-DBCO is widely used in labeling and conjugation of biomolecules, such as proteins, antibodies, and peptides. The bifunctional nature of this linker allows for efficient and site-specific attachment of different molecules, preserving their biological activity. This aids in the development of diagnostic assays and targeted therapeutic agents.
Drug Delivery: TCO-PEG24-DBCO can be employed to create targeted drug delivery systems by conjugating therapeutic agents to targeting molecules, such as antibodies or ligands. This enhances the selective delivery of drugs to specific tissues or tumor cells, minimizing side effects and increasing therapeutic efficacy. The PEG spacer in TCO-PEG24-DBCO also improves solubility and stability of the conjugates.
Biomedical Imaging: In the field of biomedical imaging, TCO-PEG24-DBCO is used to attach imaging probes, like fluorophores or radioactive isotopes, to biomolecules. This enables the precise tracking and visualization of biological processes in vivo with high sensitivity and specificity. Such conjugates are essential for disease diagnosis and monitoring treatment responses.
Biomaterials Engineering: TCO-PEG24-DBCO is applied in surface modification of biomaterials, enhancing their biocompatibility and functionality. By conjugating bioactive molecules to material surfaces, it facilitates specific cell interactions, promoting tissue integration and regeneration. This application is particularly valuable in the design of advanced medical implants and tissue engineering scaffolds.
| XLogP3 | 0.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 28 |
| Rotatable Bond Count | 80 |
| Exact Mass | 1555.87626047 g/mol |
| Monoisotopic Mass | 1555.87626047 g/mol |
| Topological Polar Surface Area | 309Ų |
| Heavy Atom Count | 109 |
| Formal Charge | 0 |
| Complexity | 2130 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Recommended Services
Recommended Articles
- Hoechst Dyes: Definition, Structure, Mechanism and Applications
- Mastering the Spectrum: A Comprehensive Guide to Cy3 and Cy5 Dyes
- Fluorescent Probes: Definition, Structure, Types and Application
- Fluorescent Dyes: Definition, Mechanism, Types and Application
- Coumarin Dyes: Definition, Structure, Benefits, Synthesis and Uses
- BODIPY Dyes: Definition, Structure, Synthesis and Uses
- Cyanine Dyes: Definition, Structure, Types and Uses
- Fluorescein Dyes: Definition, Structure, Synthesis and Uses
- Rhodamine Dyes: Definition, Structure, Uses, Excitation and Emission
- Unlocking the Power of Fluorescence Imaging: A Comprehensive Guide
- Cell Imaging: Definitions, Systems, Protocols, Dyes, and Applications
- Lipid Staining: Definition, Principles, Methods, Dyes, and Uses
- Flow Cytometry: Definition, Principles, Protocols, Dyes, and Uses
- Nucleic Acid Staining: Definition, Principles, Dyes, Procedures, and Uses
- DNA Staining: Definition, Procedures, Benefits, Dyes and Uses
- Cell Staining: Definition, Principles, Protocols, Dyes, and Uses
- Ion Imaging: Definition, Principles, Benefits, Dyes, and Uses
- Fluorescent Labeling: Definition, Principles, Types and Applications
Recommended Products
Online Inquiry
