![{[Name]}](https://resource.bocsci.com/structure/1857352-95-4.gif?v=2025011501)
![{[Name]}](/probes/images/structure-default.jpg?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/bis-sulfone-peg9-dbco.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/2093197-94-3.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/bromoacetyl-peg3-dbco.gif?v=2025011501)
Inquiry Basket
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
DBCO-PEG-Silane, MW 5,000 is a Click Chemistry polyPEG reagent. The silane group enables coupling for surface modification. This reagent can be applied to situations when copper is a concern for DBCO-activated PEGylation.
Product Specification
Application
| Storage | -20 °C |
DBCO-PEG-Silane MW 5K is a multifunctional reagent used extensively in bioconjugation and surface modification applications. Here are some key applications of DBCO-PEG-Silane MW 5K:
Surface Functionalization: DBCO-PEG-Silane MW 5K is commonly used for the functionalization of glass and silica surfaces in biosensor development. By attaching to surfaces via its silane group and presenting a DBCO group for subsequent cycloaddition reactions, it provides a versatile platform for subsequent biomolecular immobilization. This results in highly functionalized surfaces with minimal non-specific binding, essential for sensitive detection in diagnostic assays.
Nanoparticle Modification: This reagent is ideal for modifying nanoparticles with biological or chemical functionalities. The PEG spacer in DBCO-PEG-Silane helps to improve the colloidal stability of nanoparticles in biological environments, thereby reducing aggregation and non-specific interactions. The DBCO group enables bio-orthogonal conjugation with azide-functionalized molecules, allowing for targeted delivery or enhanced imaging capabilities.
Hydrogel Fabrication: DBCO-PEG-Silane is employed in the fabrication of hydrogels for tissue engineering and drug delivery systems. By incorporating this bifunctional reagent, hydrogels can be designed with specific mechanical properties and functionalities. This allows for controlled release of therapeutics or the creation of scaffolds that can mimic the extracellular matrix in cell culture applications.
Microarray Development: The use of DBCO-PEG-Silane in microarray fabrication enhances the immobilization of biomolecules on glass slides. This reagent provides a stable attachment point for DNA, RNA, or protein capture probes through bio-orthogonal click chemistry. As a result, microarrays produced with DBCO-PEG-Silane show improved sensitivity and specificity, making them more effective for high-throughput screening and diagnostic applications.
Recommended Services
Recommended Articles
- Hoechst Dyes: Definition, Structure, Mechanism and Applications
- Mastering the Spectrum: A Comprehensive Guide to Cy3 and Cy5 Dyes
- Fluorescent Probes: Definition, Structure, Types and Application
- Fluorescent Dyes: Definition, Mechanism, Types and Application
- Coumarin Dyes: Definition, Structure, Benefits, Synthesis and Uses
- BODIPY Dyes: Definition, Structure, Synthesis and Uses
- Cyanine Dyes: Definition, Structure, Types and Uses
- Fluorescein Dyes: Definition, Structure, Synthesis and Uses
- Rhodamine Dyes: Definition, Structure, Uses, Excitation and Emission
- Unlocking the Power of Fluorescence Imaging: A Comprehensive Guide
- Cell Imaging: Definitions, Systems, Protocols, Dyes, and Applications
- Lipid Staining: Definition, Principles, Methods, Dyes, and Uses
- Flow Cytometry: Definition, Principles, Protocols, Dyes, and Uses
- Nucleic Acid Staining: Definition, Principles, Dyes, Procedures, and Uses
- DNA Staining: Definition, Procedures, Benefits, Dyes and Uses
- Cell Staining: Definition, Principles, Protocols, Dyes, and Uses
- Ion Imaging: Definition, Principles, Benefits, Dyes, and Uses
- Fluorescent Labeling: Definition, Principles, Types and Applications
Recommended Products
Online Inquiry
