Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane TFA Salt

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Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane TFA Salt

Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane TFA Salt

Catalog Number R01-0071
Category Alkynes
Molecular Formula C34H56N4O12
Molecular Weight 712.8
Catalog Number Size Price Quantity
R01-0071 -- $--

Product Introduction

Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane TFA Salt is a bioactive compound with potential to combat a variety of diseases, including intractable diseases and malignancies. This compound plays a key role in facilitating drug transport mechanisms, thereby increasing the efficiency of therapeutic interventions.

Chemical Information

Purity 98%
IUPAC Name 3-[2-amino-3-[3-oxo-3-[2-(2-prop-2-ynoxyethoxy)ethylamino]propoxy]-2-[[3-oxo-3-[2-(2-prop-2-ynoxyethoxy)ethylamino]propoxy]methyl]propoxy]-N-[2-(2-prop-2-ynoxyethoxy)ethyl]propanamide
Canonical SMILES C#CCOCCOCCNC(=O)CCOCC(COCCC(=O)NCCOCCOCC#C)(COCCC(=O)NCCOCCOCC#C)N
InChI InChI=1S/C34H56N4O12/c1-4-13-42-22-25-45-19-10-36-31(39)7-16-48-28-34(35,29-49-17-8-32(40)37-11-20-46-26-23-43-14-5-2)30-50-18-9-33(41)38-12-21-47-27-24-44-15-6-3/h1-3H,7-30,35H2,(H,36,39)(H,37,40)(H,38,41)
InChI Key ZDSGMMNTGVDLQW-UHFFFAOYSA-N
  • Product Specification
  • Application
Storage -20 °C

Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane TFA Salt, a specialized reagent in chemical biology and medicinal chemistry, is a versatile tool with diverse applications.

Click Chemistry: This compound shines in click chemistry, serving as a potent agent for bioorthogonal labeling and biomolecule modification. By integrating propargyl groups, it facilitates seamless reactions with azides under gentle conditions, forming durable triazole linkages. This capability is invaluable for tagging proteins, nucleotides, and other biomolecules for intricate imaging and functional exploration.

Drug Conjugation: Leveraging Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane TFA Salt, researchers can craft drug conjugates endowed with enhanced solubility and targeted delivery prowess. The polyethylene glycol (PEG) component boosts solubility and biocompatibility of drug entities, ideal for crafting precision therapies that reach specific cell populations, curtailing undesired side effects with precision.

Surface Modification: In the domains of material science and bioengineering, this compound finds utility in surface modification, empowering researchers to imbue surfaces with tailored functional groups. By grafting onto surfaces, it enables the creation of bioactive coatings, amping up cell adhesion, protein binding, or antimicrobial attributes.

Polymer Conjugates: Capitalizing on the PEGylated structure of this reagent, scientists can forge polymer conjugates that elevate their utility for biomedical applications. Through conjugation to diverse polymers, it enhances their stability, circulation duration, and functionalization capabilities. This prowess makes it a prime candidate for augmenting drug delivery systems, diagnostic mediators, and other advanced biotechnological instruments.

Computed Properties

XLogP3 -4.1
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 13
Rotatable Bond Count 36
Exact Mass 712.38947323 g/mol
Monoisotopic Mass 712.38947323 g/mol
Topological Polar Surface Area 196Ų
Heavy Atom Count 50
Formal Charge 0
Complexity 907
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
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