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Amino-11-dUTP
| Catalog Number | R11-0002 |
| Category | Triphosphates |
| Molecular Formula | C18H62Li3N4O33P3 |
| Molecular Weight | 976.44 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R11-0002 | -- | $-- |
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Product Introduction
Amino-11-dUTP is an improved replacement for Aminoallyl dUTP. This triphosphate features longer linker, which allows for easier and more facile downstream labeling.Amino-11-dUTP is compatible with PCR, nick translation, and reverse transcription. It can be used for microarray labeling. The nucleotide is incorporated by Taq DNA polymerase, Klenow fragment, and reverse transcriptases. Subsequent reaction of amino-DNA with activated esters can be used for the labeling of DNA.
Chemical Information |
|
|---|---|
| Purity | NMR 1H and 31P, HPLC (99+%), PCR testing |
| IUPAC Name | [[[(2R,3R,5R)-5-[5-[3-(4-aminobutanoylamino)prop-1-ynyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate |
| Canonical SMILES | C1C(C(OC1N2C=C(C(=O)NC2=O)C#CCNC(=O)CCCN)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O |
| InChI | InChI=1S/C16H25N4O15P3/c17-5-1-4-13(22)18-6-2-3-10-8-20(16(24)19-15(10)23)14-7-11(21)12(33-14)9-32-37(28,29)35-38(30,31)34-36(25,26)27/h8,11-12,14,21H,1,4-7,9,17H2,(H,18,22)(H,28,29)(H,30,31)(H,19,23,24)(H2,25,26,27)/p-3/t11-,12-,14-/m1/s1 |
| InChI Key | LALQWMWAKIGPOJ-YRGRVCCFSA-K |
| Solubility | good in water |
| Appearance | colorless solid |
- Product Specification
| Storage | 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
Computed Properties | |
|---|---|
| XLogP3 | -8.8 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 16 |
| Rotatable Bond Count | 13 |
| Exact Mass | 603.02945200 g/mol |
| Monoisotopic Mass | 603.02945200 g/mol |
| Topological Polar Surface Area | 302Ų |
| Heavy Atom Count | 38 |
| Formal Charge | -3 |
| Complexity | 1150 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-6711352-B2 | Probe reagents for in situ hybridization | 2015-05-28 |
| JP-WO2016190236-A1 | Probe reagents for in situ hybridization | 2015-05-28 |
| WO-2016190236-A1 | Probe reagent for in-situ hybridization | 2015-05-28 |
| EP-3121291-A1 | Probe reagent and fish using probe reagent | 2014-03-20 |
| JP-2020089367-A | Probe reagent and FISH using the probe reagent | 2014-03-20 |
Applications of Fluorescent Probes & Dyes
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