8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt

What We Offer

8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt

8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt | 6358-69-6

Catalog Number A15-0017
Category pH Indicators
Molecular Formula C16H7Na3O10S3
Molecular Weight 524.39
Catalog Number Size Price Quantity
A15-0017 -- $--

Product Introduction

8-hydroxypyrene-1,3,6-trisulfonic acid trisodium salt is a hydrophilic, membrane-impermeant pH indicator.

Chemical Information

Related CAS 27928-00-3 (free acid)
Synonyms Pyranine concentrated; Pyranine; HPTS; Solvent Green 7; Sodium 8-hydroxypyrene-1,3,6-trisulfonate; 8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt; 1,3,6-Pyrenetrisulfonic acid, 8-hydroxy-, sodium salt (1:3); NSC 97285
Purity ≥85%
IUPAC Name trisodium;8-hydroxypyrene-1,3,6-trisulfonate
Canonical SMILES C1=CC2=C3C(=C(C=C2S(=O)(=O)[O-])S(=O)(=O)[O-])C=CC4=C(C=C(C1=C43)O)S(=O)(=O)[O-].[Na+].[Na+].[Na+]
InChI InChI=1S/C16H10O10S3.3Na/c17-11-5-12(27(18,19)20)8-3-4-10-14(29(24,25)26)6-13(28(21,22)23)9-2-1-7(11)15(8)16(9)10;;;/h1-6,17H,(H,18,19,20)(H,21,22,23)(H,24,25,26);;;/q;3*+1/p-3
InChI Key KXXXUIKPSVVSAW-UHFFFAOYSA-K
Solubility Soluble in DMSO (Sparingly, Heated), Water (Slightly)
Density 2.15 g/cm3
Appearance Yellow Solid
Boiling Point 171-178 °C at 10 mmHg (lit.)
Melting Point 62-63.5°C
LogP 4.24430
  • Product Specification
  • Application
Storage Store at 2-8°C

8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt is widely utilized in the field of biochemical assays as a fluorescent pH indicator. Its ability to undergo significant fluorescence changes in response to varying pH levels makes it an invaluable tool for monitoring pH in live-cell imaging and other biochemical experiments. This characteristic allows researchers to determine the acidity or alkalinity of cellular environments, providing critical insights into metabolic processes and cellular health. The use of this indicator in real-time applications facilitates a deeper understanding of cellular dynamics, especially in studies involving enzyme activities and metabolic pathways.

Another key application of this compound is in the development of sensor technology. 8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt is integrated into pH-sensitive sensors that are employed in environmental monitoring. These sensors can detect changes in pH levels in various aquatic environments, helping to monitor water quality and ecosystem health. By providing accurate and real-time data on pH fluctuations, this compound plays a crucial role in environmental research, assisting in the detection of pollution and the assessment of aquatic habitats.

In the realm of pharmaceuticals, 8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt serves as an important component in drug formulation and delivery systems. Its pH-responsive properties can be harnessed to design drug carriers that release therapeutic agents in a controlled manner based on the pH of the target environment. This is particularly useful in developing targeted therapies for diseases, where maintaining optimal drug release at specific pH levels enhances therapeutic efficacy and minimizes side effects. As such, its application in pharmaceutical development significantly advances the creation of smart drug delivery systems.

Lastly, the compound is frequently used in educational and research laboratories for teaching and demonstration purposes. Its vivid fluorescence and clear pH-dependent behavior provide a visually appealing and effective way to demonstrate acid-base chemistry concepts. In academic settings, students can engage with hands-on experiments using this indicator to observe pH changes in various solutions, enhancing their understanding of chemical principles. By bridging theoretical concepts with practical applications, 8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt enriches the educational experience in chemistry and biochemistry courses.

cartIcon
Inquiry Basket