2,5-Diphenyloxazole

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2,5-Diphenyloxazole

2,5-Diphenyloxazole | 92-71-7

Catalog Number A17-0124
Category Laser Dyes
Molecular Formula C15H11NO
Molecular Weight 221.25
Catalog Number Size Price Quantity
A17-0124 -- $--

Product Introduction

2,5-Diphenyloxazole is an organic scintillator, as well as a useful research chemical.

Chemical Information

Synonyms Oxazole, 2,5-diphenyl-; DPO; DPO (scintillator); NSC 24856; NSC 49168; PPO; PPO (scintillator); Tritosol
Purity ≥95%
IUPAC Name 2,5-diphenyl-1,3-oxazole
Canonical SMILES C1=CC=C(C=C1)C2=CN=C(O2)C3=CC=CC=C3
InChI InChI=1S/C15H11NO/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H
InChI Key CNRNYORZJGVOSY-UHFFFAOYSA-N
Solubility Soluble in Methanol
Density 1.128±0.06 g/cm3
Appearance White powder
Boiling Point 360°C
Melting Point 74°C
Vapor Pressure 0.00000465 [mmHg]
LogP 4.00860
  • Product Specification
  • Application
Storage Store at RT
Signal Warning
GHS Hazard Statements H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H413 (97.73%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes P264, P264+P265, P270, P273, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.)

2,5-Diphenyloxazole (PPO), an organic compound utilized in scientific research and industrial settings, boasts diverse applications. Here are four key applications of 2,5-Diphenyloxazole presented:

Scintillation Counting: A cornerstone in liquid scintillation counting, 2,5-Diphenyloxazole emerges as a premier scintillator pivotal in quantifying radioactive isotopes. When dissolved in appropriate solvents, PPO exudes light upon encountering beta particles, rendering it indispensable for discerning and measuring radioactive emissions in an array of samples spanning biological, environmental, and chemical domains.

Fluorescence Studies: Renowned for its exceptional fluorescence traits, PPO finds purpose in fluorescence microscopy and spectroscopy. Functioning as a potent fluorescent dye, it tags diverse biological molecules, enabling visualization and quantification under the discerning gaze of a fluorescence microscope. Researchers harness its capabilities to delve into cellular components, protein interactions, and other intricate molecular processes.

Clinical Diagnostics: At the forefront of medical diagnostics, 2,5-Diphenyloxazole plays a pivotal role in crafting diagnostic assays and sensors. Integrated into diagnostic kits, it aids in detecting specific biomolecules through fluorescence or scintillation techniques. This application stands as a linchpin in early disease identification, monitoring therapeutic interventions, and conducting an array of clinical assessments.

Photodegradable Polymers: Spearheading the development of photodegradable polymers, PPO aligns itself with innovative materials that disassemble upon exposure to light. These polymers can be finely tuned for specialized medical and environmental applications, such as controlled drug delivery systems and biodegradable packaging materials. The integration of PPO imbues these groundbreaking materials with the essential photodegradation attributes, propelling them towards novel frontiers.

Computed Properties

Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 2
Exact Mass 221.084063974 g/mol
Monoisotopic Mass 221.084063974 g/mol
Topological Polar Surface Area 26Ų
Heavy Atom Count 17
Formal Charge 0
Complexity 231
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Literatures

PMIDPublication DateTitleJournal
22739900 2012-06-15 Ultrabroadband femtosecond two-dimensional ultraviolet transient absorption Optics letters
22333893 2012-04-21 DNA binding and antiproliferative activity toward human carcinoma cells of copper(II) and zinc(II) complexes of a 2,5-diphenyl[1,3,4]oxadiazole derivative Dalton transactions (Cambridge, England : 2003)
22307066 2012-03-14 A femtosecond fluorescence study of vibrational relaxation and cooling dynamics of UV dyes Physical chemistry chemical physics : PCCP
22064915 2012-01-07 Application of PARAFAC to a two-component system exhibiting fluorescence resonance energy transfer: from theoretical prediction to experimental validation The Analyst
22389718 2012-01-01 Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis PloS one

Patents

Publication NumberTitlePriority Date
CN-115028759-A A laser manufacturing method based on triplet upconversion and its application 2022-06-28
CN-114891138-A A pouring method for the preparation of large volume plastic flash 2022-06-20
CN-114966805-A A method and application for rapid analysis of radionuclides based on plastic scintillation resin 2022-06-08
CN-115128659-A [14C] High-efficiency absorption scintillation fluid 2022-05-27
CN-114716830-A A kind of plastic scintillator and its preparation method and application 2022-04-14
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