N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide | CAS 109628-27-5

Catalog Number	A14-0058
Category	Calcium, Chloride and Other indicators
Molecular Formula	C17H16N2O3S
Molecular Weight	328.39

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Product Introduction

N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide is a membrane-permeant Zn2+ indicator.

Chemical Information
Product Specification
Application

Synonyms	TSQ; N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide
Canonical SMILES	CC1=CC=C(C=C1)S(=O)(=O)NC2=C3C(=CC(=C2)OC)C=CC=N3
InChI	InChI=1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3
InChIKey	HKRNYOZJJMFDBV-UHFFFAOYSA-N

Excitation	565
Emission	590

N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide is a compound of interest in bioscience research due to its versatile applications. Here are some key applications of N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide:

Fluorescent Probes: N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide can be used as a fluorescent probe in cellular imaging. Its unique fluorescent properties enable the visualization of biological molecules and cellular structures under a microscope. This application is critical for studying the spatial and temporal dynamics of cellular processes.

Enzyme Inhibition Studies: The compound is employed to study enzyme inhibition, particularly in enzymatic assays and mechanistic studies. By inhibiting specific enzymes, researchers can dissect biochemical pathways and understand enzyme functions. This knowledge is invaluable for drug discovery and therapeutic development.

Metal Ion Detection: N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide is used in the detection and quantification of metal ions in biological and environmental samples. Its chelation properties allow it to bind selectively to metal ions, causing a measurable change in fluorescence. This application is essential for monitoring metal ion concentrations and understanding their roles in various biological processes.

Pharmacological Research: The compound serves as a chemical tool in pharmacological studies to explore the effects of potential drug candidates. By targeting specific proteins or pathways, researchers can investigate the pharmacodynamics and pharmacokinetics of new compounds. This aids in the optimization and development of effective therapeutic agents.