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MAPTAM | 147504-94-7
| Catelog Number | A14-0075 |
| Category | Calcium, Chloride Indictors and Other indicators |
| Molecular Formula | C36H44N2O18 |
| Molecular Weight | 792.74 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A14-0075 | -- | $-- |
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Product Introduction
MAPTAM is a membrane-permeant calcium indicator. MAPTAM can be loaded into live cells by incubation and cleaved by cytosolic esterases to yield the fluorescent compound. It is used for investigation of the role of cytosolic calcium.
Chemical Information |
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|---|---|
| Synonyms | 1,2-bis(o-Amino-5'-methylphenoxy)ethane-N,N,N',N'-tetraacetic Acid Tetraacetoxymethyl Ester; 1,2-Bis(2-amino-5-methylphenoxy)ethane; 5,5'-Dimethyl-BAPTA-AM |
| IUPAC Name | acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-4-methylanilino]acetate |
| Canonical SMILES | CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C |
| InChI | InChI=1S/C36H44N2O18/c1-23-7-9-29(37(15-33(43)53-19-49-25(3)39)16-34(44)54-20-50-26(4)40)31(13-23)47-11-12-48-32-14-24(2)8-10-30(32)38(17-35(45)55-21-51-27(5)41)18-36(46)56-22-52-28(6)42/h7-10,13-14H,11-12,15-22H2,1-6H3 |
| InChI Key | HEOJVQZWOLQUDR-UHFFFAOYSA-N |
| Appearance | Solid Powder |
Product Specification |
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|---|---|
| Signal | Warning |
| GHS Hazard Statements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 20 |
| Rotatable Bond Count | 31 |
| Exact Mass | 792.25891256 g/mol |
| Monoisotopic Mass | 792.25891256 g/mol |
| Topological Polar Surface Area | 235Ų |
| Heavy Atom Count | 56 |
| Formal Charge | 0 |
| Complexity | 1160 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2021037869-A1 | Assessing antigen retrieval and target retrieval progression quantitation with vibrational spectroscopy | 2019-08-28 |
| EP-4022624-A1 | Assessing antigen retrieval and target retrieval progression quantitation with vibrational spectroscopy | 2019-08-28 |
| JP-2022545798-A | Assessment of antigen retrieval and target retrieval progress by vibrational spectroscopy | 2019-08-28 |
| WO-2020229578-A1 | System including a biological sample treatment chamber | 2019-05-14 |
| EP-3969876-A1 | System including a biological sample treatment chamber | 2019-05-14 |
Applications of Fluorescent Probes & Dyes
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