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Product Introduction
FAM azide, 6-isomer is a highly intricate and cutting-edge fluorescent labeling reagent renowned for its remarkable efficacy in the precise and targeted labeling of intricate biomolecules employed in the realm of biomedicine. Widely acknowledged for its unparalleled aptitude to seamlessly conjugate with proteins, nucleic acids, and peptides, particularly facilitating transformative applications like cellular imaging, flow cytometry, and ingenious drug delivery systems. By harnessing this remarkable product, scientists unlock unprecedented opportunities to decipher intricate biological processes, delving into the realms of profound protein-protein interactions and intricate cellular signaling pathways.
Chemical Information
Product Specification
Computed Properties
Patents
| Synonyms |
N-(3-azidopropyl)-3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxamide; 6-Carboxyfluorescein azide; 6-FAM-Azide min. 95 %; 4-((3-AZIDOPROPYL)CARBAMOYL)-2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)BENZOESAURE; N-(3-Azidopropyl)-3-oxo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxamide |
| Purity |
NMR 1H, HPLC-MS (95%) |
| IUPAC Name |
N-(3-azidopropyl)-3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxamide |
| Canonical SMILES |
C1=CC2=C(C=C1C(=O)NCCCN=[N+]=[N-])C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O |
| InChI |
InChI=1S/C24H18N4O6/c25-28-27-9-1-8-26-22(31)13-2-5-16-19(10-13)24(34-23(16)32)17-6-3-14(29)11-20(17)33-21-12-15(30)4-7-18(21)24/h2-7,10-12,29-30H,1,8-9H2,(H,26,31) |
| InChIKey |
JQDJGCPZDAATOX-UHFFFAOYSA-N |
| Solubility |
soluble in polar organic solvents (DMF, DMSO, alcohols) |
| Appearance |
yellowish crystals |
| ε, L⋅mol-1⋅cm-1 |
75000 |
| Fluorescence Quantum Yield |
0.9 |
| Excitation |
494 |
| Emission |
520 |
| Storage |
24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
| XLogP3 |
4 |
| Hydrogen Bond Donor Count |
3 |
| Hydrogen Bond Acceptor Count |
8 |
| Rotatable Bond Count |
5 |
| Exact Mass |
458.12263431 g/mol |
| Monoisotopic Mass |
458.12263431 g/mol |
| Topological Polar Surface Area |
119Ų |
| Heavy Atom Count |
34 |
| Formal Charge |
0 |
| Complexity |
821 |
| Isotope Atom Count |
0 |
| Defined Atom Stereocenter Count |
0 |
| Undefined Atom Stereocenter Count |
0 |
| Defined Bond Stereocenter Count |
0 |
| Undefined Bond Stereocenter Count |
0 |
| Covalently-Bonded Unit Count |
1 |
| Compound Is Canonicalized |
Yes |
| Publication Number |
Title |
Priority Date |
| US-2020190045-A1 |
Ferroportin inhibitors and methods of use |
2018-12-13 |
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