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EGTA acetoxymethyl ester | 99590-86-0
| Catelog Number | A14-0086 |
| Category | Calcium, Chloride Indictors and Other indicators |
| Molecular Formula | C26H40N2O18 |
| Molecular Weight | 668.6 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A14-0086 | -- | $-- |
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Product Introduction
EGTA acetoxymethyl ester is a cell-permeant form of EGTA, a calcium chelator. This indicator has been used for detecting intracellular calcium.
Chemical Information |
|
|---|---|
| Synonyms | EGTA/AM; EGTA AM; EGTA tetra(acetoxymethyl ester) |
| IUPAC Name | acetyloxymethyl 2-[[2-(acetyloxymethoxy)-2-oxoethyl]-[2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]ethoxy]ethoxy]ethyl]amino]acetate |
| Canonical SMILES | CC(=O)OCOC(=O)CN(CCOCCOCCN(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C |
| InChI | InChI=1S/C26H40N2O18/c1-19(29)39-15-43-23(33)11-27(12-24(34)44-16-40-20(2)30)5-7-37-9-10-38-8-6-28(13-25(35)45-17-41-21(3)31)14-26(36)46-18-42-22(4)32/h5-18H2,1-4H3 |
| InChI Key | GNJXVFXIDHCCKR-UHFFFAOYSA-N |
Computed Properties | |
|---|---|
| XLogP3 | -0.4 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 20 |
| Rotatable Bond Count | 33 |
| Exact Mass | 668.22761243 g/mol |
| Monoisotopic Mass | 668.22761243 g/mol |
| Topological Polar Surface Area | 235Ų |
| Heavy Atom Count | 46 |
| Formal Charge | 0 |
| Complexity | 857 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22406549 | 2012-03-11 | VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission | Nature neuroscience |
| 22803094 | 2012-02-01 | Role of stored calcium in the regulation of neurotransmitter quantum size | Bulletin of experimental biology and medicine |
| 21355886 | 2011-05-01 | ATP signalling is crucial for the response of human keratinocytes to mechanical stimulation by hypo-osmotic shock | Experimental dermatology |
| 21199863 | 2011-03-04 | The Ca2+-dependent phosphatase calcineurin controls the formation of the Carma1-Bcl10-Malt1 complex during T cell receptor-induced NF-kappaB activation | The Journal of biological chemistry |
| 21170054 | 2011-01-01 | Ca(2+)-dependent enhancement of release by subthreshold somatic depolarization | Nature neuroscience |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114748682-A | Composition for preparing burn wound dressing and preparation and preparation method thereof | 2022-04-26 |
| CN-114748683-A | Composition for preparing burn wound dressing and preparation and preparation method thereof | 2022-04-26 |
| CN-114831967-A | Broad-spectrum antioxidant silk fibroin band-aid and its preparation and application | 2022-04-26 |
| CN-114832144-A | Broad-spectrum antibacterial and antioxidant silk fibroin band-aid and its preparation and application | 2022-04-26 |
| WO-2022253910-A1 | A new method to treat an inflammatory skin disease | 2021-06-02 |
Applications of Fluorescent Probes & Dyes
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