Coelenterazine hcp

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Coelenterazine hcp

Coelenterazine hcp | 123437-32-1

Catelog Number A14-0062
Category Calcium, Chloride Indictors and Other indicators
Molecular Formula C25H25N3O2
Molecular Weight 399.48
Catalog Number Size Price Quantity
A14-0062 -- $--

Product Introduction

Coelenterazine hcp is a fluorescent calcium indicator that has a 190 times higher luminescence intensity with a faster response time than native coelenterazine.

Chemical Information

Synonyms CLZN hcp; 2-Benzyl-8-(cyclopentylmethyl)-6-(4-hydroxyphenyl)-7H-imidazo[1,2-a]pyrazin-3-one
IUPAC Name 2-benzyl-8-(cyclopentylmethyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3-ol
Canonical SMILES C1CCC(C1)CC2=NC(=CN3C2=NC(=C3O)CC4=CC=CC=C4)C5=CC=C(C=C5)O
InChI InChI=1S/C25H25N3O2/c29-20-12-10-19(11-13-20)23-16-28-24(21(26-23)14-17-8-4-5-9-17)27-22(25(28)30)15-18-6-2-1-3-7-18/h1-3,6-7,10-13,16-17,29-30H,4-5,8-9,14-15H2
InChI Key UCSBOFLEOACXIR-UHFFFAOYSA-N

Product Specification

Signal Warning
GHS Hazard Statements H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.)

Computed Properties

XLogP3 6.4
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 5
Exact Mass 399.19467705 g/mol
Monoisotopic Mass 399.19467705 g/mol
Topological Polar Surface Area 70.6Ų
Heavy Atom Count 30
Formal Charge 0
Complexity 541
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
WO-2022250108-A1 Phenyl urea derivative 2021-05-26
US-2022373540-A1 Reagent kit containing polypeptide for use in detection of intermolecular interactions 2021-05-19
US-2022396830-A1 Bioluminescent detection of dna synthesis 2021-05-13
WO-2022241249-A1 Bioluminescent detection of dna synthesis 2021-05-13
WO-2022232195-A2 Covalent aptamers 2021-04-26
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