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Coelenterazine 400a | 70217-82-2
| Catelog Number | A14-0006 |
| Category | Calcium, Chloride Indictors and Other indicators |
| Molecular Formula | C26H21N3O |
| Molecular Weight | 391.5 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A14-0006 | -- | $-- |
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Product Introduction
Coelenterazine 400a is a derivative of coelenterazine that produces chemiluminescence displayed by the Aequorin protein in the presence of Ca2+. It is used in BRET study as an indicator for intracelluar Ca2+.
Chemical Information |
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|---|---|
| Synonyms | 6-phenyl-2,8-bis(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one; BlueSyn C |
| Purity | ≥95% |
| IUPAC Name | 2,8-dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3-ol |
| Canonical SMILES | C1=CC=C(C=C1)CC2=C3N=C(C(=O)N3C=C(N2)C4=CC=CC=C4)CC5=CC=CC=C5 |
| InChI | InChI=1S/C26H21N3O/c30-26-23(17-20-12-6-2-7-13-20)28-25-22(16-19-10-4-1-5-11-19)27-24(18-29(25)26)21-14-8-3-9-15-21/h1-15,18,27H,16-17H2 |
| InChI Key | MWOYPGFRXPPBOX-UHFFFAOYSA-N |
| Appearance | Solid Powder |
Product Specification |
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|---|---|
| Emission | 395 nm |
| Storage | Store at -20°C |
Computed Properties | |
|---|---|
| XLogP3 | 6.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 5 |
| Exact Mass | 391.168462302 g/mol |
| Monoisotopic Mass | 391.168462302 g/mol |
| Topological Polar Surface Area | 50.4Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 524 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2022373540-A1 | Reagent kit containing polypeptide for use in detection of intermolecular interactions | 2021-05-19 |
| US-2022396830-A1 | Bioluminescent detection of dna synthesis | 2021-05-13 |
| EP-4089413-A1 | Method for determining the binding of an antibody to the complement component 1q (c1q) | 2021-05-12 |
| WO-2022238486-A1 | Method for determining the binding of an antibody to the complement component 1q (c1q) | 2021-05-12 |
| JP-2022123828-A | Polypeptide having luciferase activity | 2021-02-12 |
Applications of Fluorescent Probes & Dyes
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